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Increased circulating IgE concentration
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HP_0003212 |
[An abnormally increased overall level of immunoglobulin E in blood.] |
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Oligoclonal elevated circulating IgE concentration
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HP_0032338 |
[An increase in circulating IgE characterized by two or more bands in serum electrophoresis but not the broad diffuse band that characterizes a polyclonal increase in circulating immunoglobulins.] |
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Monoclonal elevated circulating IgE concentration
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HP_0032337 |
[An increase in circulating IgE characterized by one predominant band in serum electrophoresis but not the broad diffuse band that characterizes a polyclonal increase in circulating immunoglobulins.] |
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Increased circulating specific IgE antibody concentration
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HP_0032336 |
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Femoral artery duplication
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HP_0034998 |
[A developmental defect characterized by the presence of a supernumerary femoral artery.] |
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Abnormal femoral artery morphology
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HP_0035012 |
[Any structural abnormality of the femoral artey, a large blood vessel that provides oxygenated blood to lower extremity structures and in part to the lower anterior abdominal wall.] |
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Intracellular accumulation of collagen VII
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HP_0034999 |
[Collagen VII is the major molecular constituent of anchoring fibrils in the skin. Collagen VII is synthesized as three identical pro-alpha1(VII) polypeptide chains, which are hydroxylated and glycosylated in a coordinated manner and then fold into triple-helical procollagen VII in the endoplasmic reticulum (ER). Mature collagen VII undergoes a multistep fibril polymerization process to form the anchoring fibrils. Mutant pro-alpha1(VII) polypeptide chains or procollagen VII molecules do not pass the ER quality control and are retained in the ER or designated for ubiquitin-proteasome degradation resulting in reduced amounts of collagen VII in the skin.] |
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Asymmetric, linear skin defects
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HP_0007398 |
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Axillary apocrine gland hypoplasia
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HP_0007397 |
[Developmental hypoplasia of the apocrine sweat glands in the region of the axilla.] |
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Early cutaneous photosensitivity
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HP_0007396 |
[Photosensitivity of the skin occurring early in life.] |
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Postnatal-onset ichthyosiform erythroderma
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HP_0007395 |
[A type of ichthyosiform erythroderma with postnatal onset.] |
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Prominent superficial blood vessels
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HP_0007394 |
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Shoulder abduction contracture
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HP_0034990 |
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Shoulder external rotation contracture
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HP_0034991 |
[A type of shoulder contracture characterized by decreased internal rotation of shoulder, that is, by a chronic reduction in active and passive ability to internally rotate the humerus at the shoulder joint (if the arm is flexed at the elbow, Internal rotation of the shoulder rotates the forearm towards the center of the body).] |
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Thumb adduction contracture
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HP_0034992 |
[A type of thumb contracture characterized by a chronic reduction in active and passive ability of the metacarpal-phalangeal and/or interphalangeal joints of the thumb to bring from medial side to neutral position, where the neutral position for the thumb is when the distal and proximal segments of the thumb joint are in linear alignment.] |
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Hip internal rotation contracture
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HP_0034993 |
[The inability to rotate the proximal or upper limb segment laterally past anatomic neutral moving away from the midline, when viewed from anteriorly. Anatomic neutral position is defined as the trans-epicondylar axis of the distal humerus (for upper extremity) or femur (for lower extremity) is parallel to the sagittal plane of the body. This type of contracture is characterized by a turning of the knee from a neutral position to one facing more the midline, where the neutral position for the hip is with knee pointing directly anteriorly (less than or equal to 45 degrees).] |
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obsolete Elevated circulating saccharopine concentration
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HP_0034994 |
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Reduced tissue fructose-1,6-bisphosphatase activity
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HP_0034995 |
[Activity of fructose-1,6-bisphosphatase (EC 3.1.3.11) below the lower limit of normal. The activity can be measured in multiple tissues including liver and leukocytes.] |
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Reduced hepatic carbamoylphosphate synthetase 1 activity
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HP_0034996 |
[Activity of carbamoylphosphate synthetase 1 in the liver below the lower limit of normal.] |
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Reduced intraepidermal small nerve fiber density
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HP_0034997 |
[Reduced number of small nerve fibers in the skin.] |