All terms in HP

Label Id Description
pulmonary neuroendocrine cell CL_1000223 [A neuroendocrine cell that is part of respiratory epithelium of the lung and is involved in the sensory detection of environmental stimuli, including hypoxia, nicotine and air pressure. Ultrastructurally, this cell type is characterized by the presence of cytoplasmic dense core granules, which are considered the storage sites of amine and peptide hormones. Pulmonary neuroendocrine cells are innervated and appear as solitary cells or as clustered masses, localized at airway bifurcation sites, called neuroepithelial bodies that can release serotonin in response to hypoxia and interact with sensory nerve terminals. Pulmonary neuroendocrine cells also function as reserve stem cells that repair the surrounding epithelium after injury.]
sensory epithelial cell CL_0000098 [A specialized epithelial cell involved in sensory perception. Restricted to special sense organs of the olfactory, gustatory, and vestibulocochlear receptor systems; contain sensory cells surrounded by supportive, non-receptive cells.]
chemoreceptor cell CL_0000206 [A cell specialized to detect chemical substances and relay that information centrally in the nervous system. Chemoreceptors may monitor external stimuli, as in taste and olfaction, or internal stimuli, such as the concentrations of oxygen and carbon dioxide in the blood.]
serotonin secreting cell CL_0000458 [A cell type that secretes 5-Hydroxytryptamine (serotonin).]
neuronal receptor cell CL_0000006 [Any sensory receptor cell that is a(n) neuron and is capable of some detection of stimulus involved in sensory perception.]
Abnormal neoplastic cell morphology HP_0020162 [A morphological abnormality of of tumor or neoplastic cells, characterized by atypical size, shape, cytoplasmic or nuclear features, or other deviations from normal cellular architecture.]
Histopathological abnormality HP_0020092 [Any microscopic alteration in the cellular or tissue morphology of a biospecimen, identified through histologic examination, including changes in differentiation, organization, or cytologic features.]
Cilioretinal arteriolar hypoperfusion HP_0020163 [Ischemia in the territory of the cilioretinal artery causing opacification of the inner retina and visual loss. This is most commonly seen in central retinal vein occlusion in the young.]
Retinal arterial occlusion HP_0025326 [Blockage of the retinal artery, generally associated with interruption of blood flow and oxygen delivery to the retina.]
Ophthalmic artery occlusion HP_0020164 [Acute complete obstruction of the ophthalmic artery (branch of the internal carotid artery) that may lead to severe ischemia of the affected globe and associated ocular tissues. It can present with a similar picture to central retinal artery occlusion associated with choroidal ischemia.]
Branch retinal vein occlusion HP_0020165 [Blockage of a branch of the retinal vein. It may present with sudden-onset of painless vision loss or visual field defect correlating to the area of perfusion of the obstructed vessels.]
Central retinal vein occlusion HP_0020166 [Central retinal vein occlusion is an occlusion of the main retinal vein posterior to the lamina cribrosa of the optic nerve and is typically caused by thrombosis.]
Hemiretinal vein occlusion HP_0020167 [A variant of central retinal vein occlusions that involves the superior or inferior half of the retina.]
Tumor signet ring cell HP_0020168 [A signet ring has a flattened surface at the top of the ring with an engraved or raised symbol, historically used to stamp a seal into correspondence. Comparatively, these cells acquire a signet cell morphology due to accumulation of abundant mucin in cytoplasm, leading to nuclei dislocation to the periphery.]
Breakthrough pain HP_0032149 [A episode of severe pain that breaks through (i.e., temporarily exacerbates) a period of persistent pain.]
Congenital facial diplegia HP_0007188 [Facial diplegia (that is, bilateral facial palsy) with congenital onset.]
Facial diplegia HP_0001349 [Facial diplegia refers to bilateral facial palsy (bilateral facial palsy is much rarer than unilateral facial palsy).]
Focal lissencephaly HP_0007187 [A congenital absence of the convolutions of the cerebral cortex and a poorly formed sylvian fissure that affects a particular part of the cortex.]
GM1-ganglioside accumulation HP_0020160 [Cellular accumulation of GM1 gangliosides.]
Ganglioside accumulation HP_0004345 [Defects in the lysosomal glycosidases or specific co-activators, result in accumulation of the substrates, such as glycosphingolipids, including gangliosides in GM1 gangliosidosis (Tay-Sachs disease) and GM2 gangliosidosis (Sandhoff disease).]