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Decreased circulating alpha-mannosidase activity
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HP_0034712 |
[Concentration or activity of alpha mannosidase below the lower limit of normal in the blood circulation.] |
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Abnormal circulating alpha mannosidase activity
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HP_4000201 |
[Concentration or activity of alpha mannosidase outside of the limits of normal in the blood circulation.] |
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Abnormal hepatocyte morphology
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HP_0034713 |
[A structural anomaly of the hepatocyte, which is the main cell type that makes up the liver perncyhma. Hepatocytes are usually binucleated and appear as sheets in the liver tissue.] |
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Hepatic melanin-like lysosomal pigmentation
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HP_0034714 |
[Accumulation of dark, coarsely granular pigment localized in lysosomes of centrilobular hepatocytes.] |
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Temporal cortical atrophy
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HP_0007112 |
[Atrophy of the temporal cortex.] |
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Reduced uroporphyrinogen decarboxylase activity
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HP_0034715 |
[Activity of the enzyme uroporphyrinogen decarboxylase (UROD; EC 4.1.1.37) below the lower limit of normal.] |
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Chronic hepatic encephalopathy
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HP_0007111 |
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Reduced heme oxygenase activity
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HP_0034716 |
[Activity of the enzyme heme oxygenase below the lower limit of normal.] |
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Central hypoventilation
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HP_0007110 |
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Swollen achromatic neurons in the cerebral cortex
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HP_0034717 |
[The presence of enlarged and swollen neurons that lack Nissl bodies (the rough endoplasmic reticulum-achromasia refers to neurons that lack Nissl bodies) in the cortex of the brain.] |
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Vacuolated hepatocytes
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HP_0034718 |
[Presence of vacuoles (membrane-bound organelles that areempty of cytoplasm, lined with a membrane, and filled with fluid) in hepatocytes, which normally rarely contain vacuoles.] |
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Pilonidal sinus
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HP_0010769 |
[A sinus in the coccygeal region (the region of the intergluteal cleft). A pilonidal sinus often contains hair and skin debris.] |
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Iliac horns
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HP_0009780 |
[Horn-like malformations of the iliac crests with symmetrical bilateral central posterior iliac processes. A characteristic finding in the Nail-Patella syndrome. Iliac horns are visible on X-ray and may be palpable, but are asymptomatic.] |
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Irregular iliac crest
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HP_0003796 |
[Irregularity of the iliac crest, which is the superior border of the wing of the ilium.] |
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Lack of oocyte pronucleus formation
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HP_0034719 |
[An abnormality of oocyte maturation characterized by the inability of oocytes to form pronuclei after in vitro fertilization procedures. Oocytes normally show two pronuclei 17 to 20 hours after in vitro insemination.] |
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Abnormal female meiosis
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HP_0033338 |
[Anomalous oocyte meiosis] |
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Aplasia/Hypoplasia of toe
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HP_0001991 |
[Absence or hypoplasia of toes.] |
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Patchy sclerosis of hand bones
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HP_0004286 |
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Low insertion of columella
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HP_0010763 |
[Insertion of the posterior columella below the nasal base.] |
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Abnormal placental membrane morphology
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HP_0011409 |
[Structural anomaly of the fetal membranes (also known as the amniochorionic or placental membranes), which comprise a vital intrauterine compartment, where they perform mechanical, immune, and endocrine functions to promote growth of the fetus and protection from environmental adversity. Amniochorionic membranes anatomically consist of a single layer of cuboidal amnion epithelial cells, chorionic trophoblasts, and scattered fibroblasts connected by a layer of type IV collagen-rich extracellular matrix.] |