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endothelial cell of hepatic sinusoid
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CL_1000398 |
[An endothelial cell that is part of the hepatic sinusoid. These cells possess flattened areas containing perforations about 0.1 micrometers in diameter, known as fenestrae. The fenestrae are arranged in groups known as sieve plates.] |
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endothelial cell
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CL_0000115 |
[An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal. In mammals, endothelial cell has vimentin filaments and is derived from the mesoderm.] |
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endothelial cell of sinusoid
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CL_0002262 |
[An endothelial cell that lines any of the venous cavities through which blood passes in various glands and organs such as the spleen and liver.] |
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Placental mesenchymal dysplasia
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HP_0032165 |
[Placental mesenchymal dysplasia is a rare anomaly characterized by placentomegaly, dilatation of chorionic vessels and hydropic stem villi with cistern-like formation. It is often clinically mistaken for a partial hydatidiform mole but there is no trophoblastic proliferation. P57 immunohistochemical expression is discordant, showing a normal positive expression in the cytotrophoblastic cells, and loss of expression in the stromal cells.] |
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Increased blood folate concentration
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HP_0032164 |
[An elevated circulating concentration of folic acid, which is also known as vitamin B9.] |
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Abnormal blood folate concentration
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HP_0040087 |
[Any deviation from the normal concentration of folate in the blood circulation.] |
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Molluscum contagiosum
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HP_0032163 |
[Molluscum contagiosum is a cutaneous viral infection that is commonly observed in both healthy and immunocompromised children. The infection is caused by a member of the Poxviridae family, the molluscum contagiosum virus. Molluscum contagiosum presents as single or multiple small white or flesh-colored papules that typically have a central umbilication. The central umbilication may be difficult to observe in young children and, instead, may bear an appearance similar to an acneiform eruption. The lesions vary in size (from 1 mm to 1 cm in diameter) and are painless, although a subset of patients report pruritus in the area of infection. On average, 11-20 papules appear on the body during the course of infection and generally remains a self-limiting disease. However, in immunosuppressed patients, molluscum contagiosum can be a severe infection with hundreds of lesions developing on the body. Extensive eruption is indicative of an advanced immunodeficiency state.] |
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Reduced drug efficacy
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HP_0020173 |
[Decreased response to a drug intervention in comparison to the expected response.] |
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Abnormal drug response
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HP_0020169 |
[An anomalous response to a medication related to individual variation in metabolic or immune response to drugs varying from potentially from potentially life-threatening adverse drug reactions to alteration of therapeutic efficacy.] |
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Refractory drug response
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HP_0020174 |
[Absent or significantly reduced efficacy of drug intervention characterized by lack of measurable benefit or deterioration of disease course.] |
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Reduced circulating cholinesterase activity
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HP_0020175 |
[Activity or concentration of cholinesterase in the blood circulation below the lower limit of normal.] |
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Cholesterol crystalluria
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HP_0020176 |
[The presence of cholesterol crystals in the urine.] |
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Abnormal proportion of CD8-positive TEMRA T cells
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HP_0020177 |
[An abnormal proportion of CD8-positive, alpha-beta effector memory RA TEMRA T cells compared to the total number of T cells in the blood. These cells have the phenotype CD45RA-positive, CD45RO-negative, and CCR7-negative.] |
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Abnormal memory CD8+ T cell proportion
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HP_0410380 |
[Abnormal increase or decrease of the memory CD8+ T cell subpopulation, commonly characterized as CD45RA-, CD45RO+, or CD27-, measured as percentage of total CD8+ T cells in the blood, compared to a reference range for a given sex and age-group.] |
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Abnormal dendritic cell count
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HP_0020178 |
[A deviation from the normal count of dendritic cells in the peripheral blood circulation. Dendritic cells are of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation. These cells are lineage negative (CD3-negative, CD19-negative, CD34-negative, and CD56-negative).] |
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Increased blood drug concentration
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HP_0020170 |
[High plasma concentration of a drug as compared to previously measured thresholds given the expected concentration for the applied dosage regime.] |
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Decreased blood drug concentration
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HP_0020171 |
[Low plasma concentration of a drug as compared to previously measured thresholds given the expected concentration for the applied dosage regime.] |
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Adverse drug response
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HP_0020172 |
[An unpleasant or harmful reaction resulting from treatment with a drug.] |
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Episodic eosinophilia
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HP_0032151 |
[Recurrent episodes of marked eosinophilia that resolve spontaneously.] |
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Increased total eosinophil count
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HP_0001880 |
[Increased count of eosinophils in the blood.] |