All terms in HP

Label Id Description
bilirubin(2-) CHEBI_57977 [A dicarboxylic acid dianion obtained by deprotonation of the two carboxy groups of bilirubin; major species at pH 7.3.]
Reduced protein S activity HP_0004855 [An abnormality of coagulation related to a decreased concentration of vitamin K-dependent protein S. Protein S is a cofactor of protein C.]
Abnormality of the protein C anticoagulant pathway HP_0030780 [An anomaly of the protein C anticoagulant pathway, which serves as a major system for controlling thrombosis, limiting inflammatory responses, and potentially decreasing endothelial cell apoptosis in response to inflammatory cytokines and ischemia. A natural anticoagulant system denoted the protein C pathway exerts its anticoagulant effect by regulating the activity of FVIIIa and FVa. The vitamin K-dependent protein C is the key component of the pathway. Activated protein C (APC) cleaves and inhibits coagulation cofactors FVIIIa and FVa, which result in downregulation of the activity of the coagulation system. The endothelial protein C receptor stimulates the T-TM-mediated activation of protein C on the endothelial cell surface. The two cofactors, protein S and the intact form of FV, enhance the anticoagulant activity of APC.]
Reduced leukocyte alkaline phosphatase HP_0004852 [Decreased alkaline phosphatase measured within leukocytes.]
Low alkaline phosphatase HP_0003282 [Abnormally reduced serum levels of alkaline phosphatase.]
Recurrent deep vein thrombosis HP_0004850 [Repeated episodes of the formation of a blot clot in a deep vein.]
Deep venous thrombosis HP_0002625 [Formation of a blot clot in a deep vein. The clot often blocks blood flow, causing swelling and pain. The deep veins of the leg are most often affected.]
Folate-responsive megaloblastic anemia HP_0004851 [A type of megaloblastic anemia (i.e., anemia characterized by the presence of erythroblasts that are larger than normal) that improves upon the administration of folate.]
Megaloblastic anemia HP_0001889 [Anemia characterized by the presence of erythroblasts that are larger than normal (megaloblasts).]
phosphate(3-) CHEBI_18367 [A phosphate ion that is the conjugate base of hydrogenphosphate.]
phosphate ion CHEBI_35780 [A phosphorus oxoanion that is the conjugate base of phosphoric acid.]
type 2 immune response GO_0042092 [An immune response which is associated with resistance to extracellular organisms such as helminths and pathological conditions such as allergy, which is orchestrated by the production of particular cytokines, most notably IL-4, IL-5, IL-10, and IL-13, by any of a variety of cell types including T-helper 2 cells, eosinophils, basophils, mast cells, and nuocytes, resulting in enhanced production of certain antibody isotypes and other effects.]
immune response GO_0006955 [Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.]
T cell proliferation GO_0042098 [The expansion of a T cell population by cell division. Follows T cell activation.]
Amegakaryocytic thrombocytopenia HP_0004859 [Thrombocytopenia related to lack of or severe reduction in the count of megakaryocytes.]
Pulmonary embolism HP_0002204 [An embolus (that is, an abnormal particle circulating in the blood) located in the pulmonary artery and thereby blocking blood circulation to the lung. Usually the embolus is a blood clot that has developed in an extremity (for instance, a deep venous thrombosis), detached, and traveled through the circulation before becoming trapped in the pulmonary artery.]
Abnormality of pulmonary circulation HP_0030875 [A functional anomaly of that portion of the cardiosvascular system that carries deoxygenated blood from the heart to the lungs and returns oxygenated blood back to the heart.]
Respiratory paralysis HP_0002203 [Inability to move the muscles of respiration.]
Weakness of muscles of respiration HP_0004347 [Reduced function of the muscles required to generate subatmospheric pressure in the thoracic cavity during breathing: the diaphragm, the external intercostal and the interchondral part of the internal intercostal muscles.]
Paralysis HP_0003470 [Paralysis of voluntary muscles means loss of contraction due to interruption of one or more motor pathways from the brain to the muscle fibers. Although the word paralysis is often used interchangeably to mean either complete or partial loss of muscle strength, it is preferable to use paralysis or plegia for complete or severe loss of muscle strength, and paresis for partial or slight loss. Motor paralysis results from deficits of the upper motor neurons (corticospinal, corticobulbar, or subcorticospinal). Motor paralysis is often accompanied by an impairment in the facility of movement.]