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Growth abnormality
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HP_0001507 |
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Delayed epiphyseal ossification
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HP_0002663 |
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Abnormal epiphyseal ossification
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HP_0010656 |
[An abnormality of the formation and mineralization of an epiphysis.] |
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Autosomal recessive inheritance
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HP_0000007 |
[A mode of inheritance that is observed for traits related to a gene encoded on one of the autosomes (i.e., the human chromosomes 1-22) in which a trait manifests in individuals with two pathogenic alleles, either homozygotes (two copies of the same mutant allele) or compound heterozygotes (whereby each copy of a gene has a distinct mutant allele).] |
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Osteosarcoma
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HP_0002669 |
[A malignant bone tumor that usually develops during adolescence and usually affects the long bones including the tibia, femur, and humerus. The typical symptoms of osteosarcoma comprise bone pain, fracture, limitation of motion, and tenderness or swelling at the site of the tumor.] |
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Sarcoma
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HP_0100242 |
[A connective tissue neoplasm formed by proliferation of mesodermal cells. Bone and soft tissue sarcomas are the main types of sarcoma. Sarcoma is usually highly malignant.] |
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Abnormality of the female genitalia
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HP_0010460 |
[Abnormality of the female genital system.] |
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alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (human)
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PR_Q10469 |
[An alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase that is encoded in the genome of human.] |
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alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
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PR_000010379 |
[A protein that is a translation product of the human MGAT2 gene or a 1:1 ortholog thereof.] |
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Tall stature
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HP_0000098 |
[A height above that which is expected according to age and gender norms.] |
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Glomerulonephritis
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HP_0000099 |
[Inflammation of the renal glomeruli.] |
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Abnormal renal corpuscle morphology
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HP_0031263 |
[Any anomalous structure of the renal corpuscle, which is the initial component of the nephron that filters blood. The renal corpuscle consists of a knot of capillaries (glomerulus) that is surrounded by a double-walled capsule (Bowman capsule) that opens into a renal tubule.] |
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Glomerular sclerosis
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HP_0000096 |
[Accumulation of scar tissue within the glomerulus.] |
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Focal segmental glomerulosclerosis
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HP_0000097 |
[Segmental accumulation of scar tissue in individual (but not all) glomeruli.] |
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Nephronophthisis
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HP_0000090 |
[Presence of cysts at the corticomedullary junction of the kidney in combination with tubulointerstitial fibrosis.] |
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Abnormal renal tubule morphology
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HP_0000091 |
[An abnormality of the renal tubules.] |
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Abnormal nephron morphology
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HP_0012575 |
[A structural anomaly of the nephron.] |
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Renal tubular atrophy
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HP_0000092 |
[The presence of renal tubules with thick redundant basement membranes, or a reduction of greater than 50% in tubular diameter compared to surrounding non-atrophic tubules.] |
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Abnormal renal tubular epithelial morphology
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HP_0032599 |
[Any structural anomaly of the renal tubular epithelial cells (RTEC), a layer of cells in the outer layer of the renal tubule. These cells play a role in the absorption of substances such as glucose and amino from the primary urine.] |
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Proteinuria
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HP_0000093 |
[Increased levels of protein in the urine.] |