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Wide sacroiliac joint
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HP_6000875 |
[Distance between the sacrum and the ilium bones of the pelvis at the sacroiliac joint is above the upper limit of normal.] |
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Delayed ossification of the clavicle
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HP_6000874 |
[Delayed maturation and calcification of the clavicle.] |
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Anti-dachshund family transcription factor 1 antibody positivity
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HP_6000877 |
[The presence of autoantibodies in the serum that react against dachshund-homolog 1 (DACH1) autoantigen.] |
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Anti-Glutamate Receptor delta2 antibody positivity
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HP_6000876 |
[The presence of autoantibodies in the serum that react against glutamate receptor delta2.] |
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Anti-regulator of G protein signaling 8 antibody positivity
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HP_6000879 |
[The presence of autoantibodies in the serum that react against regulator of G-protein signaling 8 (RGS8).] |
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Anti-potassium channel tetramerization domain containing 16 antibody positivity
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HP_6000878 |
[The presence of autoantibodies (immunoglobulins) in the blood circulation that react against potassium channel tetramerization domain containing 16 (KCTD16).] |
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Abnormal B cell proliferation
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HP_0031380 |
[Any abnormality in the multiplication or reproduction of B cells, which results in the expansion of a cell population.] |
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Abnormal lymphocyte proliferation
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HP_0031378 |
[Any abnormality in the multiplication or reproduction of lymphocytes, which results in the expansion of a cell population.] |
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Abnormal T cell proliferation
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HP_0031379 |
[Any abnormality in the multiplication or reproduction of T cells, which results in the expansion of a cell population.] |
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Megakaryocyte nucleus hyperlobulation
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HP_0031388 |
[The presence of megakaryocytes in the bone marrow whose nuclei are more lobulated than expected for the size of the nucleus.] |
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Increased micromegakaryocyte count
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HP_0031386 |
[The presence of abnormally high numbers of micromegakaryocytes in the bone marrow. Micromegakaryocytes are mononuclear diploid cells, with a nucleus similar in size to that of a myeloblast or promyelocyte with the cell being less than 30 micrometers in diameter.] |
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Increased multinucleated megakaryocyte count
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HP_0031387 |
[The presence of abnormally high numbers of multinucleated megakaryocytes in the bone marrow.] |
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Reduced T cell CD40 expression
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HP_0031384 |
[A deficiency in the expression of the CD40 ligand on the surface of activated T-lymphocytes.] |
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Megakaryocyte nucleus hypolobulation
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HP_0031385 |
[The presence of megakaryocytes in the bone marrow whose nuclei are less lobulated than expected for the size of the nucleus.] |
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Decreased anti-CD3/28-induced T-cell proliferation
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HP_0031382 |
[Abnormal decrease of T cell proliferation in response to anti-CD3/28 stimulation. This is commonly measured through intracellular expression of Ki67, decreasing surface expression of carboxyfluorescein diacetate (CFSE), or 3H-thymidine incorporation. Length of incubation and strength of stimulation may vary between laboratories.] |
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Diminished tissue very long-chain acyl-CoA dehydrogenase activity
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HP_6000860 |
[Diminished activity of Very long-chain acyl-CoA dehydrogenase (VLCAD), an enzyme that catalyzes the initial step of mitochondrial beta-oxidation of long-chain fatty acids with a chain length of 14 to 20 carbons. VLCAD activity can be measured with biochemical testing using cultured fibroblasts or lymphocytes.] |
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Parotid adenoma
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HP_6000862 |
[A benign tumor of the parotid salivary gland.] |
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Diminished tissue glycogen branching enzyme activity
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HP_6000861 |
[Activity of glycogen branching enzyme in tissues below the lower limit of normal. The activity can be measured in multiple tissues including culutured fibroblasts.] |
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Transverse smile
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HP_6000864 |
[Inability to raise the corners of the mouth during the act of smiling due to facial muscle weakness. The act of smiling is accompanied by a horizontal movement of the mouth.] |
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Elevated serum-ascites albumin gradient (SAAG)
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HP_6000863 |
[An elevation of the serum ascites albumin gradient (SAAG), which is based on the difference between the albumin level of serum and of ascitic fluid, may be used to assess the extent of ascites. The SAAG is thought to reflect the colloid osmotic pressure gradient and the degree of portal hypertension. It has been shown that SAAG is a better discriminator of portal hypertension than ascites. A SAAG of 1.1 gm/dL or higher is considered as high, indicating the presence of portal hypertension, while SAAG less than 1.1 gm/dL is low, indicating the absence of portal hypertension.] |