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Rest limb pain
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HP_6000627 |
[Rest pain is a continuous unrelenting pain due to ischemia of the lower leg, beginning with or being aggravated by elevation and being relieved by sitting with legs in a dependent position or by standing.] |
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Nipple thickening
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HP_6000629 |
[Thickening of the skin around the nipple.] |
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Femoral spur
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HP_0031171 |
[A bony projection (spur, osteophyte) originating from the femur, often in the medial femoral neck.] |
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Sectoral retinitis pigmentosa
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HP_0031172 |
[A variant of retinitis pigmentosa in which there is a regional distribution of the retinal degeneration.] |
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Female fetal virilization
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HP_0031170 |
[Fetal masculinization of female external genitalia.] |
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Nuchal rigidity
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HP_0031179 |
[Resistance of the extensor muscles of the neck to being bent forwards (i.e., impaired neck flexion) as a result of muscle spasm of the extensor muscles of the neck. Nuchal rigidity is not a fixed rigidity. Nuchal rigidity has been used as a bedside test for meningism, although its sensitivity for this purpose has been debated.] |
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Finger flexor weakness
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HP_0031177 |
[Reduced ability to flex (bend) the fingers. This can manifest as incomplete closure of the hand due to weakness in finger flexion.] |
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Fixed head retroflexion
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HP_0031178 |
[Head is bent in the posterior direction in a permanent fashion.] |
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Absent cervical vertebra
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HP_0031175 |
[A developmental defect characterized by agenesis of one or more vertebral bodies of the cervical spine.] |
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Absent thoracic vertebra
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HP_0031176 |
[A developmental defect characterized by agenesis of one or more vertebral bodies of the thoracic spine.] |
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Tibial spur
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HP_0031173 |
[A bony projection (spur, osteophyte) originating from the tibia.] |
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Double-layered patella
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HP_0031174 |
[An anomaly of the patella characterized by two layers visible on lateral knee X-ray such that one layer is in front of the other in the sagittal orientation (See Figure 2A and 3B of PMID:12966518). This finding persists into adulthood.] |
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Elevated circulating chitotriosidase activity
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HP_6000611 |
[Increased activity or concentration of the enzyme chitotriosidase. Serum chitotriosidase is a biomarker that has shown high specificity and sensitivity in patients with sarcoidosis.] |
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Elevated erythrocyte galactose-1-phosphate concentration
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HP_6000610 |
[Concentration of galactose-1-phosphate in red blood cells (erythrocytes) above the upper level of normal.] |
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Enlarged fetal lungs
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HP_6000613 |
[The size (volume) of the lungs of a fetus above the upper limit of normal for the gestational age.] |
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Squamosal suture synostosis
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HP_6000612 |
[Premature closure of the squamosal suture, which is one of the lateral minor skull sutures, separating the parietal and squamous temporal bones.] |
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Reduced Inositol polyphosphate 5-phosphatase OCRL-1 activity in cultured fibroblasts
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HP_6000615 |
[Concentration or activity of inositol polyphosphate 5-phosphatase OCRL-1 as measured in cultured fibroblasts is below the limits of normal. This enzyme has phosphoinositide 5-phosphatase (EC 3.1.3.36) activity.] |
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Orbital inflammation
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HP_6000614 |
[An inflammatory condition localized to the orbit, presenting capillary dilatation, leukocytic infiltration, redness, heat, and pain. CT or MIR Imaging demonstrates enlargement of the muscle belly of one (or more) extraocular muscles typically with the involvement of tendinous insertions. Inflammation can also be observed in surrounding tissues, including the orbital fat, lacrimal gland, and optic nerve sheath.] |
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Reduced tissue UDP-glucuronyl-transferase activity
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HP_6000617 |
[Concentration or activity of uridine diphosphate glucuronosyltransferase below the lower limit of normal. The activity of this enzyme can be measured in liver and rarely in other tissues.] |
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Reduced muscle glycogen debrancher enzyme activity
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HP_6000616 |
[Activity of the gycogen debrancher enzyme (GDE) in muscle tissue is below the lower limit of normal. GDE is a large monomeric protein with two catalytic activities: amylo-1,6-glucosidase (EC 3.2.1.33) and 4-alpha-glucanotransferase (EC 2.4.1.25).] |