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Reduced tissue gamma-glutamyltransferase activity
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HP_6000578 |
[Activity of gamma-glutamyltransferase in the tissues below the lower limit of normal. The activity can be measured in multiple tissues including leukocytes and cultured fibroblasts.] |
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Reduced tissue 3-methylglutaconyl-CoA hydratase activity
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HP_6000577 |
[Activity of the mitochondrial enzyme 3-methylglutaconyl-CoA hydratase (EC 4.2.1.18) in tissues below the lower limit of normal. The activity can be measured in multiple tissues including culutured fibroblasts.] |
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Progressive cervical vertebral spine fusion
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HP_0008449 |
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Hypoplastic coccygeal vertebrae
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HP_0008447 |
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Cervical spinal canal stenosis
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HP_0008445 |
[An abnormal narrowing of the cervical spinal canal.] |
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Posterior wedging of vertebral bodies
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HP_0008444 |
[An abnormality of the shape of vertebrae, such that they are wedge-shaped (narrow towards the back).] |
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Neuropathic spinal arthropathy
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HP_0008443 |
[A progressive disorder of vertebral joint degeneration that occurs in the setting of any condition characterized by decreased afferent innervation, involving loss of deep pain and proprioceptive sensation in the vertebral column. Patients most commonly present with symptoms of lower back pain, sitting imbalance, progressive spinal deformity (usually kyphosis), and an audible clicking sound on changing postures.] |
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Vertebral hyperostosis
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HP_0008442 |
[Excessive growth of the bones of the vertebral bodies.] |
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Herniation of intervertebral nuclei
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HP_0008441 |
[The presence of one or more herniated nucleus pulposus of intervertebral disk.] |
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alpha,beta-unsaturated ketone
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CHEBI_51721 |
[A ketone of general formula R(1)R(2)C=CR(3)-C(=O)R(4) (R(4) =/= H) or R(1)C#C-C(=O)R(2) (R(2) =/= H) in which the ketonic C=O function is conjugated to an unsaturated C-C bond at the alpha,beta position.] |
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Reduced tissue thymidine phosphorylase activity
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HP_6000570 |
[Activity of thymidine phosphorylase (EC 2.4.2.4) in the tissues below the lower limit of normal. The activity can be measured in multiple tissues including leukocytes.] |
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Reduced tissue arginine:glycine amidinotransferase activity
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HP_6000572 |
[Activity of L-arginine:glycine amidinotransferase (GATM; EC 2.1.4.1) in the tissues below the lower limit of normal. GATM activity can be measured in multiple tissues including leukocytes and cultured fibroblasts.] |
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Reduced tissue tripeptidyl peptidase 1 activity
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HP_6000571 |
[Activity of tripeptidyl peptidase 1 (TPP1;EC 3.4.14.9) in the tissues below the lower limit of normal. TTP1 activity can be measured in tissues including fibroblasts and leukocytes muscle.] |
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Reduced sepiapterin reductase activity in cultured fibroblasts
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HP_6000563 |
[Activity of sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase; EC 1.1.1.153) below the lower limit of normal in cultured fibroblasts.] |
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Reduced circulating adenosine deaminase-2 activity
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HP_6000562 |
[Concentration of adenosine deaminase 2 in the blood circulation below the lower limit of normal.] |
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Elevated circulating cholesterol sulfate concentration
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HP_6000565 |
[The concentration of cholesterol sulfate in the blood circulation is above the upper limit of normal.] |
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Elevated circulating vasoactive intestinal peptide concentration
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HP_6000564 |
[The concentration of vasoactive intestinal peptide (VIP) in the blood circulation is above the upper limit of normal.] |
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5-aminolevulinate
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CHEBI_12109 |
|
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Elevated circulating oxalate concentration
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HP_6000567 |
[The concentration of oxalate in the blood circulation is above the upper limit of normal.] |
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Elevated circulating lipoprotein-X concentration
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HP_6000566 |
[The concentration of lipoprotein-X in the blood circulation is above the upper limit of normal.] |