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Hypoplasia of the iris dilator muscle
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HP_0008345 |
[Underdevelopment of the dilatator pupillae.] |
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Postprandial hyperlactemia
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HP_0011997 |
[Abnormally increased level of blood lactate following a meal.] |
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Increased circulating lactate concentration
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HP_0002151 |
[Abnormally increased level of blood lactate (2-hydroxypropanoic acid). Lactate is produced from pyruvate by lactate dehydrogenase during normal metabolism. The terms lactate and lactic acid are often used interchangeably but lactate (the component measured in blood) is strictly a weak base whereas lactic acid is the corresponding acid. Lactic acidosis is often used clinically to describe elevated lactate but should be reserved for cases where there is a corresponding acidosis (pH below 7.35).] |
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Elevated circulating branched chain amino acid concentration
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HP_0008344 |
[Concentration of a branched chain amino acid in the blood above the upper limit of normal.] |
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Postprandial hyperglycemia
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HP_0011998 |
[An increased concentration of glucose in the blood following a meal.] |
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Abnormal leukocyte physiology
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HP_0033796 |
[A functional abnormality of a white blood cell.] |
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Atrial septal dilatation
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HP_0011995 |
[A bulging of the interatrial septum towards one side. In adults, atrial septal aneurysm can be defined as a protrusion of the aneurysm of >10 mm beyond the plane of the atrial septum as measured by transesophageal echocardiography.] |
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Elevated coagulation factor V activity
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HP_0011996 |
[Increased activity of coagulation factor V, Factor V, which is activated to factor Va by means of minute amounts of thrombin (and inactivated by larger amounts of thrombin). Activated factor V (fVa) is a cofactor in the formation of the prothrombinase complex.] |
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Impaired neutrophil bactericidal activity
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HP_0011993 |
[A reduction in the ability of neutrophils to kill bacteria.] |
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Fibrous crescent
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HP_0033319 |
[A type of glomerular crescent characterized by extracapillary fibrosis composed of greater than 75% matrix and of less than 25% cells with or without fibrin, usually associated with disruption of Bowman's capsule and involving over 10% of the capsular circumference.] |
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Glomerular crescent formation
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HP_0033316 |
[Glomerular crescent refers hyperplastic lesions involving 10% or more of the circumference of Bowman's capsule. Crescents can be composed of a variable mixture of epithelial/leukocyte hypercellularity, fibrous matrix, and fibrin.] |
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Fibrocellular crescent
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HP_0033318 |
[A type of glomerular crescent characterized by extracapillary hypercellularity of more than 2 cell layers and involving over 10% of the capsular circumference, composed of 25% to 75% cells with or without fibrin, and the remainder fibrous matrix.] |
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Cellular crescent
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HP_0033317 |
[A type of glomerular crescent characterized by extracapillary hypercellularity of greater than two cell layers and involving more than 10% of the capsular circumference, composed of greater than 75% cells with or without fibrin, and less than 25% fibrous matrix.] |
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Abnormal Bowman space morphology
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HP_0033312 |
[Structural anomaly located in Bowman's space, which represents the beginning of the urinary space and is contiguous with the proximal convoluted tubule of the nephron.] |
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Visceral epithelial hyaline droplets
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HP_0033315 |
[Round to ovoid, Periodic acid-Schiff (PAS)-positive, fuchsinophilic cytoplasmic inclusions within visceral epithelial cells.] |
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Hyperprolinemia
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HP_0008358 |
[An increased concentration of proline in the blood.] |
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obsolete Combined hyperlipidemia
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HP_0008356 |
|
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Factor X activation deficiency
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HP_0008354 |
[Reduced ability to transform factor X into its activated form factor Xa.] |
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Neutral hyperaminoaciduria
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HP_0008353 |
[The presence of an abnormally increased concentration of neutral amino acids in the urine. The neutral amino acids are tryptophan, alanine, asparagine, glutamine, histidine, isoleucine, leucine, phenylalanine, serine, threonine, tyrosine and valine.] |
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Impaired platelet adhesion
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HP_0008352 |
[An abnormality of adhesion of thrombocytes. Normally, platelets adhere to collagen in the vascular subendothelium within seconds of injury via a receptor made up of glycoprotein Ia and IIa and GPVI and to vWF via receptor GPIb/IX/V. The adherent platelets then release granules that lead to platelet activation and aggregation.] |