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Decreased circulating beta-carotene concentration
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HP_0430073 |
[The concentration of beta-carotene in the blood circulation is below the lower limit of normal.] |
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Mammary blocked duct
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HP_0430075 |
[Blocked mammary ducts represent an area of localized milk stasis, typically associated with breast engorgement and resulting in a localized tender breast lump or area of blushed color; the breast may feel hot; and there may be a white, painful bleb on the end of the nipple.] |
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blood coagulation, common pathway
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GO_0072377 |
[A protein activation cascade that contributes to blood coagulation and consists of events leading from the formation of activated Factor Xa by either the intrinsic or extrinsic pathway, to the formation of active thrombin, the cleavage of fibrinogen by thrombin, and the formation of cleaved fibrin into a stable multimeric, cross-linked complex.] |
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blood coagulation, fibrin clot formation
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GO_0072378 |
[A protein activation cascade that contributes to blood coagulation and consists of the cascade of enzymatic reactions initiated by physical damage to the wall of a blood vessel, leading to the formation of a formation of a fibrin clot at the site of the injury. The process also includes numerous positive and negative regulatory events.] |
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valeric acid
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CHEBI_17418 |
[A straight-chain saturated fatty acid containing five carbon atoms.] |
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Calcaneal apophysitis
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HP_6001351 |
[Inflammation of the calcaneal apophysis (bony projection where the Achilles tendon attaches to the heel). Lateral foot x-ray shows increased density in the calcaneal apophysis or fragmentation of the apophysis.] |
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Positive heel squeeze test
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HP_6001350 |
[The squeeze test is the most common examination for diagnosing calcaneal apophysitis (Sever disease) and is conducted by compressing the medial and lateral aspects of the calcaneus. The test is considered positive (abnormal) if squeezing elicits pain.] |
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Elevated circulating C-triol concentration
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HP_6001353 |
[The concentration of cholestane-3beta, 5alpha, 6beta-triol (C-triol) in the blood circulation is above the upper limit of normal. C-triol is a diagnostic biomarker for Niemann-Pick disease type C.] |
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negative regulation of cell maturation
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GO_1903430 |
[Any process that stops, prevents or reduces the frequency, rate or extent of cell maturation.] |
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Decreased circulating guanidinoacetic acid concentration
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HP_6001352 |
[The concentration of guanidinoacetic acid in the blood circulation is below the lower limit of normal.] |
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Fifth metatarsal apophysitis
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HP_6001344 |
[Iselin's disease is a traction apophysitis of base of fifth metatarsal. The apophysis is within the peroneus brevis tendon insertion site and appears radiographically at about age 10 in female and age 12 in male and usually fuses by age 11 in female and by age 14 in male. Repetitive microtrauma from the peroneus brevis tendon, as occurs in sports activities is the cause of traction apophysitis. It can be ascertained by oblique foot radiographs showing apophyseal irregularity (enlarged apophysis, disordered ossification, widened chondro-osseous junction) at the base of the fifth metatarsal.] |
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Anti-schistosoma antibody positivity
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HP_0430089 |
[The presence of antibodies in the blood circulation that react against a component of a parasite of the genus Schistosomiasis is a parasitic disease historically known as bilharzia caused by the trematode of the genus Schistosoma. Schistosomiasis is a parasitic disease historically known as bilharzia caused by the trematode of the genus Schistosoma.] |
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Peroneal tendon tear
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HP_6001343 |
[Injury to a peroneal tendon, as can be ascertained by an MRI study of the ankle showing partial or complete tear of one or both of the peroneal tendons.] |
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positive regulation of cell maturation
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GO_1903431 |
[Any process that activates or increases the frequency, rate or extent of cell maturation.] |
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Anti-measles antibody positivity
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HP_0430088 |
[The presence of antibodies in the blood circulation that react against a component of measles virus.] |
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Enteric anendocrinosis
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HP_6001346 |
[Near absence of small intestinal and colonic endocrine cells. This feature can be ascertained histopathologically and may also be manifested as a lack of staining for enteroendocrive markers such as synaptophysin.] |
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Tibial tubercle apophysitis
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HP_6001345 |
[Lateral knee radiograph showing tibial tuberosity apophysis irregularity and fragmentation; tibial tubercle osteochondrosis; traction apophysitis of the tibial tubercle.] |
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Hallux sesamoiditis
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HP_6001348 |
[Inflammation of the sesamoid bones of the hallux ( two ovoid-shaped ossicles embedded within the tendons under the big toe). This feature can be ascertained by MRI of the foot, revealing edema within one or both of the hallux sesamoids.] |
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Metatarsal head osteochondrosis
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HP_6001347 |
[Avascular necrosis of a metatarsal head, most commonly involving the second, but also the third or fourth, metatarsal.
Comment: Affected individuals may present with foot pain on weight-bearing, swelling, and tenderness. Radiological features include widening of the metatarsophalangeal joint space and flattening of the affected metatarsal head, at later stages metatarsal head sclerosis, cortical thickening, and intra-articular loose bodies. Osteochondrosis is a condition resulting from an epiphysis injury that alters enchondral ossification and produces irregularity at the joint surface. Freiberg disease is characterized as osteochondrosis of the metatarsal heads (primarily the second).] |
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Os trigonum
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HP_6001349 |
[Os trigonum (OT) is one of the most common accessory ossicles in the foot and ankle region. In clinical practice, OT is a considerable factor that may predispose patients to posterior ankle impingement syndrome (PAIS). Lateral ankle x-ray with foot in plantarflexion reveals an accessory ossicle at the posterior aspect of the talus, between the posterior distal tibia and calcaneal tuberosity.] |