All terms in HP

Label Id Description
preBCR-negative large pre-B-II cell CL_0000953 [A pre-BCR-negative large pre-B-II cell is a large pre-B-II cell that is pre-B cell receptor-negative, composed of surrogate light chain protein (SL), which is composed of VpreB and Lambda 5/14.1, in complex with immunoglobulin mu heavy chain (IgHmu), on the cell surface, and lack a DNA rearrangement of immunoglobulin light chain genes.]
large pre-B-II cell CL_0000957 [A large pre-B-II cell is a pre-B-II cell that is proliferating and is Rag1-negative and Rag2-negative.]
preBCR-positive large pre-B-II cell CL_0000952 [An preBRC-positive large pre-B-II cell is a large pre-B-II cell that is pre-B cell receptor-positive, composed of surrogate light chain protein (SL), which is composed of VpreB , Lambda 5/14.1, in complex with immunoglobulin mu heavy chain (IgHmu) on the cell surface.]
T2 B cell CL_0000959 [A transitional stage B cell that has the phenotype surface IgM-positive, surface IgD-postive, CD21-positive, CD23-positive, CD62L-negative, CD93-positive and is located in the splenic B follicles. This cell type has also been described as IgM-high, CD19-positive, B220-positive, AA4-positive, and CD23-positive.]
transitional stage B cell CL_0000818 [An immature B cell of an intermediate stage between the pre-B cell stage and the mature naive stage with the phenotype surface IgM-positive and CD19-positive, and are subject to the process of B cell selection. A transitional B cell migrates from the bone marrow into the peripheral circulation, and then to the spleen.]
T1 B cell CL_0000958 [A transitional stage B cell that migrates from the bone marrow into the peripheral circulation, and finally to the spleen. This cell type has the phenotype surface IgM-positive, surface IgD-negative, CD21-negative, CD23-negative, and CD62L-negative, and CD93-positive. This cell type has also been described as IgM-high, CD19-positive, B220-positive, AA4-positive, and CD23-negative.]
Activating thyroid-stimulating hormone receptor defect HP_0011790 [Gain-of-function thyroid-stimulating hormone receptor (TSHR) defect.]
pre-B-I cell CL_0000956 [A pre-B-I cell is a precursor B cell that expresses CD34 and surrogate immunoglobulin light chain (VpreB , Lambda 5 (mouse)/14.1 (human)) on the cell surface, and TdT, Rag1,and Rag2 intracellularly. Cell type carries a D-JH DNA rearrangement, and lacks expression of immunglobulin heavy chain protein.]
Bm2 B cell CL_0000962 [A follicular B cell that is IgD-positive and CD23-positive and CD38-positive. This naive cell type is activated in the extrafollicular areas via interaction with dendritic cells and antigen specific T cells.]
follicular B cell CL_0000843 [A resting mature B cell that has the phenotype IgM-positive, IgD-positive, CD23-positive and CD21-positive, and found in the B cell follicles of the white pulp of the spleen or the corticol areas of the peripheral lymph nodes. This cell type is also described as being CD19-positive, B220-positive, AA4-negative, CD43-negative, and CD5-negative.]
Bm1 B cell CL_0000961 [A follicular B cell that is IgD-positive, CD23-negative, and CD38-negative. This naive cell type is activated in the extrafollicular areas through interaction with interdigitating dendritic cells and antigen-specific CD4-positive T cells.]
fraction F mature B cell CL_0002056 [A mature B cell subset originally defined as having being CD45R-positive, IgM-positive, IgD-positive and CD43-negative. Subsequent research demonstrated being CD21-positive and CD23-negative and CD93 negative.]
Elevated right ventricular systolic pressure HP_0033119 [Elevation of right ventricular systolic pressure (RVSP) above normal limits. In adults, RVSP is normally 20-30 mmHg.]
Duodenitis HP_0033117 [Inflammation of the lining of the upper small intestine (duodenum).]
Hyperapobetalipoproteinemia HP_0008158 [Hyperapobetalipoproteinemia is defined as the combination of a normal low density lipoprotein (LDL) cholesterol in the face of an increased LDL apolipoprotein B (apoB) protein.]
Periodic hypokalemic paresis HP_0008153 [Episodes of muscle weakness associated with reduced levels of potassium in the blood.]
Decreased circulating cortisol level HP_0008163 [Abnormally reduced concentration of cortisol in the blood.]
Asymptomatic hyperammonemia HP_0008162 [An increased concentration of ammonia in the blood not associated with symptoms such as encephalopathy.]
Absent leukocyte alkaline phosphatase HP_0008161 [Alkaline phosphatase levels measured within leukocytes is below detectable levels.]
3-hydroxydicarboxylic aciduria HP_0008160 [The concentration of 2-hydroxydicarboxylic acid in the urine, normalized for urine concentration, is above the upper limit of normal.]