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Upper motor neuron dysfunction
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HP_0002493 |
[A functional anomaly of the upper motor neuron. The upper motor neurons are neurons of the primary motor cortex which project to the brainstem and spinal chord via the corticonuclear, corticobulbar and corticospinal (pyramidal) tracts. They are involved in control of voluntary movements. Dysfunction leads to weakness, impairment of fine motor movements, spasticity, hyperreflexia and abnormal pyramidal signs.] |
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Abnormal corticospinal tract morphology
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HP_0002492 |
[Abnormality of the corticospinal tract, which is the chief element of the pyramidal system (the principle motor tract) and is the only direct connection between the cerebrum and the spinal cord.] |
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Abnormal pyramidal tract morphology
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HP_0002062 |
[Any structural abnormality of the pyramidal tract, whose chief element, the corticospinal tract, is the only direct connection between the brain and the spinal cord. In addition to the corticospinal tract, the pyramidal system includes the corticobulbar, corticomesencephalic, and corticopontine tracts.] |
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Impaired vibratory sensation
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HP_0002495 |
[A decrease in the ability to perceive vibration. Clinically, this is usually tested with a tuning fork which vibrates at 128 Hz and is applied to bony prominences such as the malleoli at the ankles or the metacarpal-phalangeal joints. There is a slow decay of vibration from the tuning fork. The degree of vibratory sense loss can be crudely estimated by counting the number of seconds that the examiner can perceive the vibration longer than the patient.] |
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Abnormal rapid eye movement sleep
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HP_0002494 |
[Abnormality of REM Sleep are phases of REM sleep are characterized by desynchronized EEG patterns, increases in heart rate and blood pressure, sympathetic activation, and a profound loss of muscle tone except for the eye and middle-ear muscles. There are also phases of rapid eye movements.] |
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Microgastria
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HP_0100841 |
[A developmental anomaly with a small tubular or saccular midline stomach.] |
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obsolete Glioblastoma
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HP_0100843 |
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Spasticity of facial muscles
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HP_0002491 |
[Spasticity of one or more muscles innervated by the facial nerve.] |
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Abnormality of facial musculature
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HP_0000301 |
[An anomaly of a muscle that is innervated by the facial nerve (the seventh cranial nerve).] |
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Septo-optic dysplasia
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HP_0100842 |
[Underdevelopment of the optic nerve and absence of the septum pellucidum.] |
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Optic nerve hypoplasia
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HP_0000609 |
[Underdevelopment of the optic nerve.] |
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Absent septum pellucidum
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HP_0001331 |
[Absence of the septum pellucidum (meaning translucent wall in Latin - SP), also known as the ventricle of Sylvius. The septum pellucidum is a thin, triangular double membrane separating the frontal horns of the right and left lateral ventricles of the brain. It extends between the anterior portion of the corpus callosum, and the body of the fornix and its width varies from 1.5 to 3.0 mm.] |
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Increased CSF lactate
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HP_0002490 |
[Increased concentration of lactate in the cerebrospinal fluid.] |
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Abnormal CSF lactate concentration
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HP_0030085 |
[Abnormal concentration of lactate in the cerebrospinal fluid.] |
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Anaphylactic shock
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HP_0100845 |
[An acute hypersensitivity reaction due to exposure to a previously encountered antigen.] |
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Pancreatic fistula
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HP_0100844 |
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Palmoplantar pustulosis
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HP_0100847 |
[A chronic, relapsing, pustular eruption that is localized to the palms and soles.] |
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Pustule
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HP_0200039 |
[A small elevation of the skin containing cloudy or purulent material usually consisting of necrotic inflammatory cells.] |
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Neoplasm of the scrotum
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HP_0100849 |
[A tumor (abnormal growth of tissue) of the scrotum.] |
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Neoplasm of the male external genitalia
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HP_0100848 |
[A tumor (abnormal growth of tissue) of the male external genitalia.] |