A serious and potentially life-threatening condition that arises when a considerable mass of body tissue dies (necrosis). [ https://www.worldcat.org/search?q=bn%3A9780781770873 ]
Synonyms: Death of body tissue due to lack of blood flow or infection
Term information
- SNOMEDCT_US:372070002
- SNOMEDCT_US:36024000
- UMLS:C0017086
This may occur after an injury or infection, or in people suffering from any chronic health problem affecting blood circulation. The prime cause of gangrene is reduced blood supply to the affected tissues, which results in cell death. Diabetes and long-term smoking increase the risk of suffering from gangrene. There are different types of gangrene with different symptoms, such as dry gangrene, wet gangrene, gas gangrene, internal gangrene and necrotising fasciitis. Treatment options include debridement (or, in severe cases, amputation) of the affected body parts, antibiotics, vascular surgery, maggot therapy or hyperbaric oxygen therapy.