A heterogeneous group of congenital spinal anomalies that result from defective closure of the neural tube early in fetal life. [ https://orcid.org/0000-0002-0736-9199 ]
Synonyms: Incomplete closure of the vertebral arch
Term information
- SNOMEDCT_US:253098009
- UMLS:C0027794
Spinal dysraphism, or neural tube defect comprises a heterogeneous group of congenital spinal anomalies that result from defective closure of the neural tube early in fetal life and anomalous development of the caudal cell mass. The anatomic features common to the entire group is an anomaly in the midline structures of the back, especially the absence of some of the neural arches, and defects of the skin, filum terminale, nerves, and spinal cord. Open forms of spinal dysraphism include myelocele, meningocele, and myelomeningocele. These open forms are often associated with hydrocephalus and Arnold-Chiari malformation type II and may be classified as spina bifida aperta. Closed forms of spinal dysraphism include spina bifida occulta.
Term relations
- has part some (
closure incomplete and
characteristic of some arch of centrum of vertebra and
has modifier some abnormal)