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Ph-positive acute lymphoblastic leukemia

Go to external page http://purl.obolibrary.org/obo/HP_0004848

A subset of acute lymphoblastic leukemia that results from a reciprocal translocation between the ABL-1 oncogene and a breakpoint cluster region (BCR), resulting in a fusion gene, BCR-ABL, that encodes an oncogenic protein with constitutively active tyrosine kinase activity. [ http://www.ncbi.nlm.nih.gov/pubmed/21472706 ]

Synonyms: Philadelphia-positive acute lymphoblastic leukaemia Ph-positive acute lymphoblastic leukaemia Philadelphia-positive acute lymphoblastic leukemia

This is just here as a test because I lose it

Term information

database cross reference
  • UMLS:C1960397
  • SNOMEDCT_US:426955004
  • SNOMEDCT_US:425688002
UK spelling
Ph-positive acute lymphoblastic leukaemia

UK spelling
Philadelphia-positive acute lymphoblastic leukaemia

id

HP:0004848

Term relations