Proto-Oncogene_Proteins_c-kit
Go to external page https://bio.scai.fraunhofer.de/ontology/GECCO_#Proto-Oncogene_Proteins_c-kit
Synonyms: CD117
This is just here as a test because I lose it
Term information
hasDefinition
A protein-tyrosine kinase receptor that is specific for STEM CELL FACTOR. This interaction is crucial for the development of hematopoietic, gonadal, and pigment stem cells. Genetic mutations that disrupt the expression of PROTO-ONCOGENE PROTEINS C-KIT are associated with PIEBALDISM, while overexpression or constitutive activation of the c-kit protein-tyrosine kinase is associated with tumorigenesis.