|
p-Phenylenediamine
|
DB14141 |
|
|
ZW-49
|
DB15472 |
[According to Zymeworks, "ZW49 is a bispecific anti-HER2 ADC that is based on the same antibody framework as [ZW25] but armed with a cytotoxic payload."[L8234] It is being investigated for several indications characterized by HER2 expression including breast and gastric cancers that have progressed or are refractory to existing HER2-targeted therapies, and other HER2 expressing solid tumors.] |
|
Dipropylene glycol
|
DB14140 |
|
|
ZW-25
|
DB15471 |
[According to Zymeworks, "ZW25 is a bispecific antibody that can simultaneously bind two non-overlapping epitopes, known as biparatopic binding, of HER2 resulting in dual HER2 signal blockade, increased binding and removal of HER2 protein from the cell surface, and potent effector function. These combined mechanisms of action have led to significant anti-tumor activity in preclinical models of breast and gastric cancers."[L8219]] |
|
Distearyldimonium
|
DB14143 |
|
|
Haemagglutinin-strain B (Yamagata)
|
DB15474 |
|
|
Haemagglutinin-strain B (Victoria)
|
DB15473 |
|
|
Methoxy PEG-12 retinamide
|
DB14142 |
|
|
Minretumomab
|
DB15470 |
|
|
9,10-Deepithio-9,10-Didehydroacanthifolicin
|
DB02169 |
[A specific inhibitor of phosphoserine/threonine protein phosphatase 1 and 2a. It is also a potent tumor promoter. (Thromb Res 1992;67(4):345-54 & Cancer Res 1993;53(2):239-41)] |
|
Mercaptomethyl Phosphonate
|
DB03498 |
|
|
N,N-Dimethyl-L-Alanine
|
DB02167 |
|
|
Malate Ion
|
DB03499 |
|
|
6-bromopurine
|
DB02168 |
|
|
Alvocidib
|
DB03496 |
[Alvocidib is a synthetic flavonoid based on an extract from an Indian plant for the potential treatment of cancer. It works by inhibiting cyclin-dependent kinases, arresting cell division and causing apoptosis in non-small lung cancer cells.] |
|
Zinc trihydroxide
|
DB02165 |
|
|
Propidium
|
DB02166 |
[Quaternary ammonium analog of ethidium; an intercalating dye with a specific affinity to certain forms of DNA and, used as diiodide, to separate them in density gradients; also forms fluorescent complexes with cholinesterase which it inhibits. [PubChem]] |
|
O-Sulfo-L-Serine
|
DB03497 |
|
|
Bromothalonil
|
DB14199 |
[Bromothalonil, also known as Methyldibromo glutaronitrile (MDBGN), is a widely used preservative that can be found in many personal hygiene and industrial products. It is also a known allergen and dermatological irritant that has been banned in many EU countries due to increasing rates of contact allergy [A34322]. In 2005, MDBGN was named in the top 15 most frequently positive allergens identified in patch tests by the North American Contact Dermatitis Group (NACDG)[A34326].
Sensitivity to Bromothalonil may be identified with a clinical patch test.] |
|
N-Cyclohexyl-N'-phenyl-1,4-phenylenediamine
|
DB14196 |
[N-Cyclohexyl-N'-phenyl-1,4-phenylenediamine is a component of black rubber. It is also a dermatological sensitizer and allergen.
Sensitivity to N-Cyclohexyl-N'-phenyl-1,4-phenylenediamine may be identified with a clinical patch test.] |
