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Niobium
|
DB13031 |
[Niobium has been used in trials studying the treatment of Obesity and Overweight.] |
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Rosa centifolia flower oil
|
DB14363 |
[Rosa centifolia flower oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.] |
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Moringa oleifera leaf
|
DB14362 |
[Moringa oleifera leaf is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.] |
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Enecadin
|
DB13032 |
[Enecadin has been investigated for the treatment of Stroke.] |
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Norfloxacin
|
DB01059 |
[A synthetic fluoroquinolone (fluoroquinolones) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA gyrase.] |
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Praziquantel
|
DB01058 |
[An anthelmintic used in most schistosome and many cestode infestations.] |
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Mimosine
|
DB01055 |
[Mimosine is an antineoplastic alanine-substituted pyridine derivative isolated from _Leucena glauca_.] |
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Cyclohexyl-{4-[5-(3,4-Dichlorophenyl)-2-Piperidin-4-Yl-3-Propyl-3h-Imidazol-4-Yl]-Pyrimidin-2-Yl}Amine
|
DB02388 |
|
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Nitrendipine
|
DB01054 |
[Nitrendipine is a calcium channel blocker with marked vasodilator action. It is an effective antihypertensive agent and differs from other calcium channel blockers in that it does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive.] |
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Echothiophate
|
DB01057 |
[A potent, long-acting irreversible cholinesterase inhibitor used as an ocular hypertensive in the treatment of glaucoma. Occasionally used for accomodative esotropia.] |
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D-threo-neopterin
|
DB02385 |
[A pteridine derivative present in body fluids; elevated levels result from immune system activation, malignant disease, allograft rejection, and viral infections. (From Stedman, 26th ed) Neopterin also serves as a precursor in the biosynthesis of biopterin.] |
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Leucine Phosphonic Acid
|
DB02386 |
|
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Tocainide
|
DB01056 |
[An antiarrhythmic agent which exerts a potential- and frequency-dependent block of sodium channels.] |
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N-Hydroxy-4-[(4-Methoxylphenyl)Sulfonyl]-2,2-Dimethyl-Hexahydro-1,4-Thiazepine-3(S)-Carboxamide
|
DB02350 |
|
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Dibenzofuran-4,6-Dicarboxylic Acid
|
DB03682 |
|
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Isosorbide mononitrate
|
DB01020 |
[Isosorbide mononitrate is a drug used principally in the treatment of angina pectoris and acts by dilating the blood vessels so as to reduce the blood pressure. It is sold by AstraZeneca under the trade name Imdur.
Isosorbide mononitrate is used to for the the prophylactic treatment of angina pectoris; that is, it is taken in order to prevent or at least reduce the occurrence of angina. Research on Isosorbide mononitrate as a cervical ripener to reduce time at hospital to birth is supportive.
Isosorbide mononitrate is an active metabolite of isosorbide dinitrate and exerts qualitatively similar effects. Isosorbide mononitrate reduces the workload of the heart by producing venous and arterial dilation. By reducing the end diastolic pressure and volume, isosorbide mononitrate lowers intramural pressure, hence leading to an improvement in the subendocardial blood flow. The net effect when administering isosorbide mononitrate is therefore a reduced workload for the heart and an improvement in the oxygen supply/demand balance of the myocardium.
The adverse reactions which follow have been reported in studies with isosorbide mononitrate:
Very common. Up to 30% of patients experience headaches and 2-3 % of patients withdraw treatment for this reason, but the incidence reduces rapidly as treatment continues .
Common. 6% of patients experience tiredness, sleep disturbances, and gastrointestinal disturbances. 4-5% of patients experience hypotension, 2.5% experience poor appetite, and 1% experience nausea.
Patients experience similar adverse effects as they would for all nitrate treatments and their incidence is most common early in treatment. These symptoms generally disappear during long-term treatment.
Other reactions that have been reported with isosorbide mononitrate modified release tablets include tachycardia, vomiting, diarrhoea, vertigo and heartburn] |
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Tartronate
|
DB03680 |
|
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2,2-bis(4-hydroxy-3-tert-butylphenyl)propane
|
DB13008 |
[TBD has been used in trials studying the treatment of Adenocarcinoma.] |
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Scutellaria lateriflora
|
DB14339 |
[Scutellaria lateriflora is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.] |
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Carbendazim
|
DB13009 |
[Carbendazim has been used in trials studying the treatment of Lymphoma and Unspecified Adult Solid Tumor, Protocol Specific.] |
