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Phenolsulfonphthalein
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DB13212 |
[Phenolsulfonphthalein or otherwise called phenol red is a pH indicator commonly used in cell biology laboratories. Phenolsulfonphthalein is being investigated for use clinically due to its weak estrogen mimicking actions [A174964].] |
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Hydrocortisone phosphate
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DB14542 |
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Chlorprothixene
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DB01239 |
[Chlorprothixene is a typical antipsychotic drug of the thioxanthene (tricyclic) class. Chlorprothixene exerts strong blocking effects by blocking the 5-HT2 D1, D2, D3, histamine H1, muscarinic and alpha1 adrenergic receptors.] |
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Aripiprazole
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DB01238 |
[Aripiprazole is an atypical antipsychotic orally indicated for treatment of schizophrenia, bipolar I, major depressive disorder, irritability associated with autism, and Tourette's[Label]. It is also indicated as an injection for agitation associated with schizophrenia or bipolar mania[Label]. Aripiprazole exerts its effects through agonism of dopaminic and 5-HT1A receptors and antagonism of alpha adrenergic and 5-HT2A receptors[Label,A4393]. Aripiprazole was given FDA approval on November 15, 2002[L6136].] |
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2',3'-Dehydro-2',3'-Deoxy-Thymidine 5'-Diphosphate
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DB02569 |
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PD173955
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DB02567 |
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3-Chloro-4-Hydroxyphenylglycine
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DB03898 |
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Levodopa
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DB01235 |
[Levodopa is a prodrug of dopamine that is administered to patients with Parkinson's due to its ability to cross the blood-brain barrier[Label]. Levodopa can be metabolised to dopamine on either side of the blood-brain barrier and so it is generally administered with a dopa decarboxylase inhibitor like carbidopa to prevent metabolism until after it has crossed the blood-brain barrier[Label,A177781]. Once past the blood-brain barrier, levodopa is metabolized to dopamine and supplements the low endogenous levels of dopamine to treat symptoms of Parkinson's[Label]. The first developed drug product that was approved by the FDA was a levodopa and carbidopa combined product called Sinemet that was approved on May 2, 1975[A177781,L6133].] |
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9-Butyl-8-(4-Methoxybenzyl)-9h-Purin-6-Amine
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DB03899 |
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Peldesine
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DB02568 |
[Peldesine is a potent inhibitor of human CCRF-CEM T-cell proliferation. It has undergone phase I trials for the treatment of Human Immunodeficiency Virus (HIV) infections.] |
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Dexamethasone
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DB01234 |
[Dexamethasone, or MK-125, is a corticosteroid fluorinated at position 9 used to treat endocrine, rheumatic, collagen, dermatologic, allergic, ophthalmic, gastrointestinal, respiratory, hematologic, neoplastic, edematous, and other conditions.[L10701] Developed in 1957, it is structurally similar to other corticosteroids like [hydrocortisone] and [prednisolone].[A188724,A188724]
Dexamethasone was granted FDA approval on 30 October 1958.[L10695]] |
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Bromodiphenhydramine
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DB01237 |
[Bromodiphenhydramine is an ethanolamine antihistamine with antimicrobial property. Bromodiphenhydramine is used in the control of cutaneous allergies. Ethanolamine antihistamines produce marked sedation in most patients.] |
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4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide
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DB02565 |
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Triphosphoric acid
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DB03896 |
[Used as water softener, peptizing agent, emulsifier & dispersing agent; ingredient of cleansers; meat preservative.] |
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Hydroxyphenyl Propionic Acid
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DB03897 |
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8-Hydroxy-4-(1-Hydroxyethyl)Quinoline-2-Carboxylic Acid
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DB02566 |
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Sevoflurane
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DB01236 |
[Sevoflurane, also called fluoromethyl, is an ether inhalation anaesthetic agent used for the induction and maintenance of general anesthesia. It is a volatile, non-flammable, non-irritant, and easy-to-administer compound with a low solubility profile and blood-to-gas partition coefficient.] |
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N-Propargyl-1(S)-Aminoindan
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DB03894 |
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Hexanoyl-CoA
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DB02563 |
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Diphenidol
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DB01231 |
[Diphenidol is an antiemetic agent used in the treatment of vomiting and vertigo. Diphenidol overdose may result in serious toxicity in children.] |
