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Colforsin
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DB02587 |
[Potent activator of the adenylate cyclase system and the biosynthesis of cyclic AMP. From the plant Coleus forskohlii. Has antihypertensive, positive inotropic, platelet aggregation inhibitory, and smooth muscle relaxant activities; also lowers intraocular pressure and promotes release of hormones from the pituitary gland.] |
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(2R)-2-[(1R)-1-{[(2S)-2-Carboxy-2-(4-hydroxyphenyl)acetyl]amino}-1-methoxy-2-oxoethyl]-5-methylene-5,6-dihydro-2H-1,3-oxazine-4-carboxylic acid
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DB02588 |
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4-(Hydroxymethyl)Benzamidine
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DB02585 |
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Ergometrine
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DB01253 |
[An ergot alkaloid with uterine and vascular smooth muscle contractile properties.] |
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4,7-Dimethyl-[1,10]Phenanthroline
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DB02586 |
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Mitiglinide
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DB01252 |
[Mitiglinide is a drug for the treatment of type 2 diabetes. It may stimulate insulin secretion in beta-cells by closing off ATP dependant potassium ion channels.] |
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Lisdexamfetamine
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DB01255 |
[Also known as _Vyvanse_, lisdexamfetamine (L-lysine-d-amphetamine) is a prodrug of the psychostimulant d-amphetamine [A40246]. It is paired with the essential amino acid _L-lysine_. Lisdexamfetamine dimesylate increases attention span and decreases restlessness in children and adults who are overactive/hyperactive, cannot concentrate for long periods, or are easily distracted or impulsive [A2230].
As a central nervous system stimulant, lisdexamfetamine is utilized as an adjunct therapy in the treatment of attention deficit hyperactivity disorder (ADHD). As a prodrug, lisdexamfetamine was specifically engineered as an abuse-resistant product [F2368]. The mechanism by which this occurs is through delayed release after ingestion (unlike some other psychostimulant drugs, which may be abused). After oral administration and absorption, enzyme hydrolysis after contact with red blood cells metabolize lisdexamfetamine into L- lysine, a naturally occurring essential amino acid and active _d-amphetamine_, which is responsible for the drug’s pharmacological effects. Gastrointestinal pH does not affect this conversion, and the addition of the L-lysine slows the amount of d-amphetamine available in the circulation and central nervous system [F2368].] |
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N6-(2,5-Dimethoxy-Benzyl)-N6-Methyl-Pyrido[2,3-D]Pyrimidine-2,4,6-Triamine
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DB02583 |
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Dasatinib
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DB01254 |
[Dasatinib is an oral dual BCR/ABL and Src family tyrosine kinase inhibitor approved for use in patients with chronic myelogenous leukemia (CML). The main targets of Dasatinib, are BCRABL, SRC, Ephrins and GFR.] |
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Batimastat
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DB03880 |
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Bamethan
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DB13206 |
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Hydrocortisone aceponate
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DB14538 |
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Chromate ion Cr-51
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DB14537 |
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Arginine glutamate
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DB13207 |
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Prednylidene
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DB13208 |
[Prednylidene is an experimental systemic glucocorticoid.] |
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Bismuth subnitrate
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DB13209 |
[Bismuth subnitrate, also referred to as bismuth oxynitrate or bismuthyl nitrate, is a highly water-soluble crystalline compound that has been used as a treatment for duodenal ulcers and anti-diarrheic agent [A33012]. The use of bismuth substrate as an active ingredient in over-the-counter antacids is approved by the FDA.] |
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Hydrocortisone acetate
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DB14539 |
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Piprozolin
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DB13202 |
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Gold cation (1+)
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DB14534 |
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Zinc chloride
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DB14533 |
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