|
Bezafibrate
|
DB01393 |
[Antilipemic agent that lowers cholesterol and triglycerides. It decreases low density lipoproteins and increases high density lipoproteins.] |
|
Albumin human
|
DB00062 |
[Human serum albumin is the primary protein present in human blood plasma. The main function of albumin is to maintain the oncotic pressure of blood [A33706]. It binds to water, cations (such as Ca2+, Na+ and K+), fatty acids, hormones, bilirubin, thyroxine (T4) and pharmaceuticals (including barbiturates). Albumin represents approximately 50% of the total protein content in healthy humans [A40060].
Human albumin is a small globular protein (molecular weight: 66.5 kDa), consisting of a single chain of 585 amino acids organized in three repeated homolog domains (sites I, II, and III). Each domain comprises two separate sub-domains (A and B) [A40060].
There are various preparations of albumin that are well established and widely available in the clinical setting [L3108], [L3109], [L3101].
Also known as _Albuminex_ 5% or 25%, one brand of human serum albumin is prepared from the pooled plasma of US donors in FDA-licensed facilities in the US [F229]. This is a biosimilar drug to existing human serum albumin and was approved for a biological license at both 5% and 25% concentrations by the FDA on June 21, 2018 [L3101].] |
|
Sodium bicarbonate
|
DB01390 |
[Sodium bicarbonate is a white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and in topical cleansing solutions.] |
|
Ganetespib
|
DB12047 |
[Ganetespib is under investigation for the treatment of BREAST CANCER, Small Cell Lung Cancer, Acute Myeloid Leukaemia, and Myelodysplastic Syndrome.] |
|
Norfenefrine
|
DB13378 |
|
|
Chiniofon
|
DB13379 |
|
|
Savolitinib
|
DB12048 |
[Savolitinib has been used in trials studying the treatment and health services research of Tumor, Food Effect, Gastric Cancer, Health Subjects, and Colorectal Cancer, among others.] |
|
Dasolampanel etibutil
|
DB12049 |
[Dasolampanel etibutil has been used in trials studying the treatment of Diabetic Neuropathy, Painful.] |
|
Vincamine
|
DB13374 |
[Vincamine is a monoterpenoid indole alkaloid obtained from the leaves of *Vinca minor* with a vasodilatory property. Studies indicate that vincamine increases the regional cerebral blood flow.] |
|
Sepetaprost
|
DB12043 |
[Sepetaprost has been used in trials studying the treatment of Open Angle-glaucoma, Ocular Hypertension, and Mild Open Angle-glaucoma (OAG).] |
|
MK-0893
|
DB12044 |
[MK0893 has been used in trials studying the treatment of Type 2 Diabetes Mellitus and Diabetes Mellitus, Type 2.] |
|
Edrecolomab
|
DB13375 |
|
|
Mericitabine
|
DB12045 |
[Mericitabine has been investigated for the treatment of Hepatitis C, Chronic.
Mericitabine is a polymerase inhibitor being developed for the treatment of chronic hepatitis C. Mericitabine is a prodrug of PSI-6130, which demonstrated excellent potency in preclinical studies. PSI-6130 is a pyrimidine nucleoside analog inhibitor of HCV RNA polymerase, an enzyme that is necessary for hepatitis C viral replication.] |
|
Succinimide
|
DB13376 |
|
|
Atopaxar
|
DB12046 |
[Atopaxar has been investigated for the treatment of Coronary Artery Disease and Acute Coronary Syndrome.] |
|
Vinbarbital
|
DB13377 |
|
|
Bromisoval
|
DB13370 |
|
|
2-octyl cyanoacrylate
|
DB12040 |
[Dermabond has been investigated for the basic science of Wound Healing.] |
|
Difenpiramide
|
DB13371 |
|
|
Mapracorat
|
DB12041 |
[Mapracorat has been investigated for the treatment of Eczema and Atopic Dermatitis.] |
