|
Digoxin Immune Fab (Ovine)
|
DB00076 |
[Digoxin Immune Fab is a sheep antibody (26-10) FAB fragment from sheep immunized with the digoxin derivative Digoxindicarboxymethylamine. It is used as an antidote for overdose of digoxin.] |
|
Muromonab
|
DB00075 |
[Murine monoclonal antibody specific to CD3 T-cell lymphocyte antigens. More specifically it is a purified murine (mouse) monoclonal antibody, directed against the CD3 (T3) receptor on the surface of human T-cells (T-lymphocytes) cultured using the murine ascites method. Muromonab is 93% monomeric immune globulin G type 2a (IgG2a).] |
|
Ibritumomab tiuxetan
|
DB00078 |
[Indium or yttrium conjugated murine IgG1 kappa monoclonal antibody directed against the CD20 antigen, which is found on the surface of normal and malignant B lymphocytes. Ibritumomab is produced in Chinese hamster ovary cells and is composed of two murine gamma 1 heavy chains of 445 amino acids each and two kappa light chains of 213 amino acids each.] |
|
Botulinum toxin type A
|
DB00083 |
[Purified botulinum toxin from Clostridium botulinum, purified from culture via dialysis and acid precipitation.] |
|
Pegvisomant
|
DB00082 |
[Pegvisomant is a highly selective growth hormone (GH) receptor antagonist. It is used to treat acromegaly. Unlike dopamine or somatostatin analogs (which inhibit growth hormone secretion), this drug actually blocks the hepatic (GH-mediated) production of insulin like growth factor (IGF-1), which is the main mediator of growth hormone activity.] |
|
Pancrelipase
|
DB00085 |
[Pancrelipase, in general, is composed of a mixture of pancreatic enzymes which include amylases, lipases, and proteases. These enzymes are extracted from porcine pancreatic glands.[L2509] The pancrelipase mixture was developed by Ortho-McNeil-Janssen Pharmaceuticals, Inc and FDA approved on April 12, 2010.[L2510] For further information on the components of this mixture please visit [DB11065], [DB11066] and [DB13147].] |
|
Tositumomab
|
DB00081 |
[Murine IgG2a lambda monoclonal antibody against CD20 antigen (2 heavy chains of 451 residues, 2 lambda chains of 220 residues). It is produced in an antibiotic-free culture of mammalian cells. It can be covalently linked to Iodine 131 (a radioactive isotope of iodine).] |
|
Daptomycin
|
DB00080 |
[Daptomycin is a naturally-occurring lipopeptide antibiotic that kills susceptible gram positive bacteria by disrupting their membrane potential. It is found in the soil bacterium called <i>Streptomyces roseosporus</i>. Antibiotics are used in the treatment of infections caused by bacteria. They work by killing bacteria or preventing their growth. Daptomycin will not work for colds, flu, or other virus infections. It was approved in September 2003 for the treatment of complicated skin and soft tissue infections. It has a safety profile similar to other agents commonly administered to treat gram-positive infections.] |
|
Sovaprevir
|
DB12069 |
[Sovaprevir has been investigated for the treatment of Hepatitis C, Chronic.] |
|
Neocitrullamon
|
DB13396 |
|
|
Radalbuvir
|
DB12065 |
[Radalbuvir has been used in trials studying the treatment of Chronic Hepatitis C, Chronic HCV Infection, and Chronic Hepatitis C Infection.] |
|
Prenoxdiazine
|
DB13397 |
|
|
Orteronel
|
DB12066 |
[Orteronel has been investigated for the treatment of Prostate Cancer.] |
|
BMS-394136
|
DB12067 |
[BMS-394136 has been used in trials studying the diagnostic of Heart Diseases.] |
|
Oxyfedrine
|
DB13398 |
|
|
Terguride
|
DB13399 |
|
|
T-900607
|
DB12068 |
[T900607 has been used in trials studying the treatment of Liver Cancer and Gastric Cancer.] |
|
Mercurochrome
|
DB13392 |
[Mercurochrome is a trade name of merbromin commonly used as a topical first-aid antiseptic agent. It is an organomercuric disodium salt compound and a fluorescein that is available in many countries, except Switzerland, France, Germany, and the United States where the drug was withdrawn from market due to the possibility of mercury poisoning.] |
|
Pardoprunox
|
DB12061 |
[Pardoprunox has been used in trials studying the treatment of Early Stage Parkinson's Disease and Advanced Stage Parkinson's Disease. Pardoprunox is a partial dopamine D2 agonist and noradrenergic agonist with serotonin 5-HT1A agonist properties.] |
|
Emetine
|
DB13393 |
|
