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Bradykinin
|
DB12126 |
[Bradykinin has been investigated for the basic science and treatment of Hypertension and Diabetes Type 2.] |
|
Oxaflozane
|
DB13457 |
|
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Thebacon
|
DB13458 |
|
|
Sultamicillin
|
DB12127 |
[Sultamicillin has been used in trials studying the prevention and treatment of Ventilator Associated Pneumonia and Chronic Obstructive Pulmonary Disease (COPD).] |
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Prasinezumab
|
DB14788 |
[Prasinezumab is under investigation in clinical trial NCT03100149 (A Study to Evaluate the Efficacy of Prasinezumab (RO7046015/PRX002) in Participants With Early Parkinson's Disease).] |
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Tioclomarol
|
DB13451 |
|
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Avoralstat
|
DB12120 |
[Avoralstat has been used in trials studying the prevention of HAE and Hereditary Angioedema.] |
|
Diroximel fumarate
|
DB14783 |
[Multiple Sclerosis (MS) is a chronic, debilitating neurological disease that can lead to profound cognitive and physical symptoms, severely affecting quality of life.[A176474] It is the main cause of neurological disability not caused by trauma in the young adult population of both North America and Europe. Relapsing-remitting forms of MS lead to neurological symptoms that resolve and recur periodically. More than 80% of patients suffering from this disease have relapsing-remitting MS.[A187535]
Diroximel fumarate is a new drug from the fumarate class formulated to treat various relapsing forms of MS. This drug is bioequivalent to [Dimethyl fumarate][A187544,L9626](initially manufactured in 2013), but is less likely to cause gastrointestinal side effects, owing to its unique chemical structure. Diroximel fumarate was formulated by Alkermes in collaboration with Biogen, and approved by the FDA on October 30, 2019.[L9626]] |
|
Tofersen
|
DB14782 |
[Tofersen is under investigation in clinical trial NCT03764488 (A Study to Evaluate Safety, Tolerability, and Distribution of a Microdose of Radiolabeled BIIB067 (99mTc-MAG3-BIIB067) Co-administered With BIIB067 to Healthy Adults).] |
|
Cadralazine
|
DB13452 |
|
|
Entospletinib
|
DB12121 |
[Entospletinib has been used in trials studying the treatment of Oncology, Follicular Lymphoma, B-cell Malignancies, Mantle Cell Lymphoma, and Non-Hodgkin Lymphoma, among others.] |
|
Fenebrutinib
|
DB14785 |
[Fenebrutinib is under investigation in clinical trial NCT03174041 (A Drug-Drug Interaction Study Between GDC-0853 and Midazolam, Itraconazole, Rosuvastatin, and Simvastatin).] |
|
Xenon
|
DB13453 |
|
|
Figopitant
|
DB12122 |
[Figopitant is under investigation in clinical trial NCT02209714 (Safety, Tolerability and Pharmacodynamics After Oral Administration of BIIF 1149 BS in Healthy Male Volunteers).] |
|
Nicomorphine
|
DB13454 |
|
|
Cinepazide
|
DB12123 |
[Cinepazide has been used in trials studying the treatment of Ischemic Stroke.] |
|
Gancotamab
|
DB14784 |
[Gancotamab is under investigation in clinical trial NCT02213744 (MM-302 Plus Trastuzumab vs. Chemotherapy of Physician's Choice Plus Trastuzumab in HER2-Positive Locally Advanced/Metastatic Breast Cancer Patients).] |
|
Vofatamab
|
DB14781 |
[Vofatamab is under investigation in clinical trial NCT02401542 (Dose Escalation, Expansion Study of Vofatamab (B-701) in Treatment of Locally Advanced or Metastatic Urothelial Cell Carcinoma).] |
|
Pegzilarginase
|
DB14780 |
[Pegzilarginase is under investigation in clinical trial NCT02488044 (A Phase 1/2 Study of AEB1102 in Patients With Arginase I Deficiency).] |
|
Leucine
|
DB00149 |
[An essential branched-chain amino acid important for hemoglobin formation.] |
