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Adenosine-5'-Pentaphosphate
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DB02738 |
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Tiotropium
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DB01409 |
[Tiotropium is a long-acting, antimuscarinic bronchodilator used in the management of chronic obstructive pulmonary disease (COPD) and asthma.[A180163,L7084,L7087,L7090,L7093] Tiotropium acts mainly on M3 muscarinic receptors located in the airways to produce smooth muscle relaxation and bronchodilation.[A180163,L7084,L7087,L7090,L7093]
Tiotropium is more specific for the subset of muscarinic receptors commonly found in the lungs than [ipratropium].[A180163]
Tiotropium was granted FDA approval on 30 January 2004.[L7084]] |
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Acetamide
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DB02736 |
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Ginseng
|
DB01404 |
[Ginseng is promoted as an adaptogen (a product that increases the body's resistance to stress), one which can to a certain extent be supported with reference to its anticarcinogenic and antioxidant properties. Ginseng is also known to contain phytoestrogens.] |
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Methotrimeprazine
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DB01403 |
[A phenothiazine with pharmacological activity similar to that of both chlorpromazine and promethazine. It has the histamine-antagonist properties of the antihistamines together with central nervous system effects resembling those of chlorpromazine. (From Martindale, The Extra Pharmacopoeia, 30th ed, p604)] |
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Danazol
|
DB01406 |
[A synthetic steroid with antigonadotropic and anti-estrogenic activities that acts as an anterior pituitary suppressant by inhibiting the pituitary output of gonadotropins. It possesses some androgenic properties. Danazol has been used in the treatment of endometriosis and some benign breast disorders.] |
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4-Deoxy-D-Mannuronic Acid
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DB02734 |
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2-Amino-3-Oxo-4-Sulfo-Butyric Acid
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DB02735 |
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Temafloxacin
|
DB01405 |
[Temafloxacin is an antibiotic agent belonging to the fluoroquinolone drug class. It was first approved for use in the U.S. market in 1992, but was withdrawn shortly due to the reports of serious adverse reactions, such as allergic reactions and hemolyric anemia, resulting in three deaths.] |
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[(2R,3S,4R,5R)-5-(4-acetonyl-3-carbamoyl-pyridin-1-ium-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] phosphate
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DB02732 |
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Neostigmine
|
DB01400 |
[A cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Neostigmine, unlike physostigmine, does not cross the blood-brain barrier.] |
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Purvalanol
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DB02733 |
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4-Methylthio-Alpha-D-Mannose
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DB02730 |
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Ethylmercurithiosalicylic acid
|
DB02731 |
[Ethylmercurithiosalicylic acid is a topical antiseptic used on skin and mucous membranes. It is also used as a preservative in pharmaceuticals.] |
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Choline magnesium trisalicylate
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DB01401 |
[Choline magnesium trisalicylate is a non-acetylated salicylate used widely as a nonsteroidal anti-inflammatory drug. Trisalicylate significantly reduces methotrexate renal clearance, displacing methotrexate from protein, increasing the fraction unbound by 28% [A19653, A19654].] |
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Rebeccamycin
|
DB14729 |
[Rebeccamycin is a weak topoisomerase I inhibitor isolated from _Nocardia sp_.] |
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Mebenil
|
DB14728 |
[An obsolete fungicide used to control various pathogens on cereals and seed potatoes.] |
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Cefamandole nafate
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DB14725 |
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Emapalumab
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DB14724 |
[Emapalumab, also known as NI-0501, is a fully human monoclonal antibody that targets interferon gamma. Emapalumab development was sponsored by NovImmune SA, further developed by Sobi and FDA approved on November 20, 2018.[A38676, L4840] The approval of emapalumab was followed by the designation of orphan drug, priority review and breakthrough therapy.[L4840] As well, emapalumab was given the status of PRIME by the EMA.[L4845]] |
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Riboflavin tetrabutyrate
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DB14727 |
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