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Clemastine
|
DB00283 |
[An ethanolamine-derivative, first generation histamine H1 antagonist used in hay fever, rhinitis, allergic skin conditions, and pruritus. It causes drowsiness.] |
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Pamidronic acid
|
DB00282 |
[Pamidronic acid (INN) or pamidronate disodium (USAN), marketed as pamidronate disodium pentahydrate under the brand name Aredia, is a bisphosphonate.] |
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Brigatinib
|
DB12267 |
[Brigatinib, originally named AP26113, is a reversible dual inhibitor of anaplastic lymphoma kinase (ALK) and epidermal growth factor receptor (EGFR). It presents selectivity against the mutant forms of EGFR compared to the wild-type.[A31311] It also exhibits selectivity against 9 different Crizotinib-resistant mutants of the EML4-ALK fusion gene, which is a pivotal player in the transformation of susceptible lung parenchyma.[A31313] Brigatinib was developed by Ariad Pharmaceuticals, a subsidiary of Takeda Pharmaceutical Company Limited, and FDA-approved on April 28, 2017.[L1026]] |
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Diethyl ether
|
DB13598 |
|
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Carmegliptin
|
DB12268 |
[Carmegliptin has been used in trials studying the treatment of Diabetes Mellitus Type 2.] |
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Difetarsone
|
DB13599 |
|
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PF-06273340
|
DB12269 |
[Pf 06273340 is under investigation in clinical trial NCT01934738 (A Study to Evaluate Safety, Toleration and Time Course of Plasma Concentration of Multiple Oral Doses of PF-06273340 in Healthy Subjects of Two AgeGroups, Aged 18-55 Years (Group 1) and Aged 56-75 Years (Group 2)).] |
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Begacestat
|
DB12263 |
[Begacestat has been used in trials studying the treatment and basic science of Alzheimer Disease.] |
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Almasilate
|
DB13595 |
[Almasilate is a buffering antacid that has been used in peptic ulcers and dyspepsia. It is a crystalline polyhydrate of aluminium/magnesium silicate and mediates its buffering activity by binding hydrogen ions within the polymer. However its therapeutic efficacy is not comparable to other approved antacids, as it is no more effective in neutralizing acid and binding bile salts than other conventional antacids [A27138].
Given that there are generally more widely available conventional antacids that are just as - if not more - effective than almasilate, almasilate products are only available in certain parts of Europe and/or Asia.] |
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Atevirdine
|
DB12264 |
[Atevirdine has been used in trials studying the treatment of HIV Infections.] |
|
Fexinidazole
|
DB12265 |
[Fexinidazole has been investigated for the treatment of Disease, Chagas and South American Trypanosomiasis.] |
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Oxycinchophen
|
DB13596 |
|
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Epofolate
|
DB12266 |
[Epofolate has been used in trials studying the treatment of Advanced Solid Tumors.] |
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Moroxydine
|
DB13597 |
|
|
Calcium pangamate
|
DB13590 |
|
|
Metopimazine
|
DB13591 |
|
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Radiprodil
|
DB12260 |
[Radiprodil has been used in trials studying the treatment of Infantile Spasms (IS) and Diabetic Peripheral Neuropathic Pain.] |
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Ascrinvacumab
|
DB12261 |
[Ascrinvacumab has been used in trials studying the treatment and basic science of Neoplasms, Advanced Solid Tumors, Carcinoma, Hepatocellular, and Malignant Pleural Mesothelioma.] |
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Etamiphylline
|
DB13592 |
|
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CRS-3123
|
DB12262 |
[CRS3123 has been used in trials studying the treatment of Clostridial Infection and Clostridium Difficile Colitis.] |
