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Solenopsis richteri
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DB11026 |
[Solenopsis richteri allergenic extract is used in allergenic testing. It is extracted from the black imported fire ant which is native to South Amercia. The species has also been introduced in North Amercia. When stung, the bites are characterized by sterile pustules that are surrounded by reddened swelling along with redness extending beyond.] |
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Quinisocaine
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DB13683 |
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Bizelesin
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DB12352 |
[Bizelesin has been used in trials studying the treatment of Unspecified Adult Solid Tumor, Protocol Specific.] |
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Dendryphiella vinosa
|
DB11025 |
[Dendryphiella vinosa is a fungus which can provoke allergic reactions. Dendryphiella vinosa extract is used in allergenic testing.] |
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Omoconazole
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DB13684 |
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Ulodesine
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DB12353 |
[Ulodesine has been used in trials studying the treatment of Gout, Arthritis, Hyperuricemia, and Joint Disease.] |
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Quingestanol
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DB13685 |
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Imrecoxib
|
DB12354 |
[Imrecoxib has been used in trials studying the treatment of Knee Osteoarthritis.] |
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Clonostachys rosea f. rosea
|
DB11024 |
[Clonostachys rosea f. rosea allergenic extract is used in allergenic testing.] |
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Naftazone
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DB13680 |
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Butalamine
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DB13681 |
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Rostafuroxin
|
DB12350 |
[Rostafuroxin has been used in trials studying the treatment of Essential Hypertension.] |
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Palonosetron
|
DB00377 |
[Palonosetron (INN, trade name Aloxi) is an antagonist of 5-HT3 receptors that is indicated for the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). It is the most effective of the 5-HT3 antagonists in controlling delayed CINV nausea and vomiting that appear more than 24 hours after the first dose of a course of chemotherapy and is the only drug of its class approved for this use by the U.S. Food and Drug Administration. As of 2008, it is the most recent 5-HT3 antagonist to enter clinical use.] |
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Trihexyphenidyl
|
DB00376 |
[One of the centrally acting muscarinic antagonists used for treatment of parkinsonian disorders and drug-induced extrapyramidal movement disorders and as an antispasmodic.] |
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Mexiletine
|
DB00379 |
[Antiarrhythmic agent pharmacologically similar to lidocaine. It may have some anticonvulsant properties.] |
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Dydrogesterone
|
DB00378 |
[A synthetic progestational hormone with no androgenic or estrogenic properties. Unlike many other progestational compounds, dydrogesterone produces no increase in temperature and does not inhibit ovulation.] |
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Timolol
|
DB00373 |
[Timolol is a nonselective beta-adrenergic antagonist given in an eye drop solution to reduce intraocular pressure, or pressure in the eyes.[L6724] It is also used in tablet form as a drug to treat hypertension.[L6727] Timolol was first approved by the FDA in 1978.[L6724] This drug is marketed by several manufacturers [L6736] and is an effective agent for the management of conditions such as open-angle glaucoma and hypertension.] |
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Thiethylperazine
|
DB00372 |
[A dopamine antagonist that is particularly useful in treating the nausea and vomiting associated with anesthesia, mildly emetic cancer chemotherapy agents, radiation therapy, and toxins. This piperazine phenothiazine does not prevent vertigo or motion sickness. (From AMA Drug Evaluations Annual, 1994, p457)] |
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Colestipol
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DB00375 |
[Bile acid sequestrants like colestipol have been in use since the 1970s.[FDA Label, F4555, F4567, L6262] And even though such an agent may very well be useful in reducing elevated cholesterol levels and decreasing the risk for atherosclerotic vascular disease due to hypercholesterolemia, colestipol is still generally only employed as an adjunct therapy and the relatively physical nature of its pharmacological activity sometimes limits its usefulness.[FDA Label, F4555, F4567, L6262]
In particular, as colestipol's general mechanism of action ultimately results in the decreased absorption and enhanced secretion of bile acids and lipids in the feces, patients who take complicated medication regimens, experience constipation or biliary obstruction, etc. may not be good candidates for using the agent owing to its physical effects on the gut.[FDA Label, F4555, F4567, L6262]
Alternatively, colestipol predominantly elicits its activities within the gut environment because it undergoes little absorption and metabolism.[FDA Label, F4555, F4567, L6262] The resultant lack of systemic exposure consequently means the medication generally demonstrates very few adverse effects inside the body.[FDA Label, F4555, F4567, L6262]] |
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Treprostinil
|
DB00374 |
[Treprostinil is a synthetic analogue of prostacyclin, used to treat pulmonary hypertension.] |
