|
1'-Deazo-Thiamin Diphosphate
|
DB01658 |
|
|
Hydromorphone
|
DB00327 |
[Hydromorphone is a pure opioid,[A176468] a semi-synthetic hydrogenated ketone derivative of [morphine] that has been available clinically since 1920. Structurally, hydromorphone derived from [morphine] in the modification of the hydroxyl group in the carbon 6 to a carbonyl and the absence of a double bond between the carbon 7 and 8. Due to these modifications, it presents a very high potency and comparable side effect profile to the parent compound.[A176471] Even though hydromorphone does not present a 6-hydroxyl group, it is categorized under the family of phenanthrenes and it is considered a chemical under the schedule II (medical purposes with high addiction potential).[A176495]
The first reported approved product containing hydromorphone in the form of hydromorphone hydrochloride was developed by Fresenius Kabi USA and FDA approved in 1984.[L5795]] |
|
8-iodo-guanine
|
DB02985 |
|
|
Floxuridine
|
DB00322 |
[An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection. Floxuridine is available as a sterile, nonpyrogenic, lyophilized powder for reconstitution. When administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.] |
|
N-(2-Thienylmethyl)-2,5-Thiophenedisulfonamide
|
DB02986 |
|
|
4-hydroxybenzoyl-CoA
|
DB01652 |
|
|
Amitriptyline
|
DB00321 |
[Amitriptyline hydrochloride, also known as _Elavil_, is a tricyclic antidepressant (TCA) with analgesic properties, widely used to treat depression and neuropathic pain [A174658]. It was originally approved by the FDA in 1977 and manufactured by Sandoz [L5308].] |
|
Fluorometholone
|
DB00324 |
[A glucocorticoid employed, usually as eye drops, in the treatment of allergic and inflammatory conditions of the eye. It has also been used topically in the treatment of various skin disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p732)] |
|
L-gulonic acid 6-phosphate
|
DB01655 |
|
|
Para-Mercury-Benzenesulfonic Acid
|
DB02983 |
|
|
4-[3-Methylsulfanylanilino]-6,7-Dimethoxyquinazoline
|
DB02984 |
|
|
Tolcapone
|
DB00323 |
[Tolcapone is a drug that inhibits the enzyme catechol-O-methyl transferase (COMT). It is used in the treatment of Parkinson's disease as an adjunct to levodopa/carbidopa medication. It is a yellow, odorless, non-hygroscopic, crystalline compound. Tolcapone is associated with a risk of hepatotoxicity.] |
|
Vitamin B6 Complexed with 2-Amino-Hexanoic Acid
|
DB02981 |
|
|
Bombykol
|
DB02982 |
|
|
Dihydroergotamine
|
DB00320 |
[A 9,10alpha-dihydro derivative of ergotamine. It is used as a vasoconstrictor, specifically for the therapy of migraine disorders.] |
|
Methyl 4,6-O-[(1R)-1-carboxyethylidene]-beta-D-galactopyranoside
|
DB01651 |
|
|
Thymidine-5'-(dithio)phosphate
|
DB02980 |
|
|
trans-2-hydroxycinnamic acid
|
DB01650 |
|
|
Phenazocine
|
DB13606 |
|
|
Flurbiprofen axetil
|
DB14938 |
[Flurbiprofen axetil is under investigation in clinical trial NCT02043366 (Effect of Butorphanol Combined With Flurbiprofen Axetil on Preventing Hyperalgesia Induced by Remifentanil in Patients).] |
