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Oxolinic acid
|
DB13627 |
|
|
MK-3577
|
DB14957 |
[MK-3577 is under investigation in clinical trial NCT00868790 (A Study of the Safety and Efficacy of MK-3577 in Participants With Type 2 Diabetes Mellitus (MK-3577-009)).] |
|
Potassium gluconate
|
DB13620 |
[Potassium gluconate is a salt of [DB01345] and is classified as a food additive by the FDA [L2654]. It is also used as a potassium supplement [L2657].
Potassium is an essential nutrient. It is the most abundant cation in the intracellular fluid, where it plays a key role in maintaining cell function [A32222].
In dietary supplements, potassium is often present as potassium chloride, but many other forms—including potassium citrate, phosphate, aspartate, bicarbonate, and **gluconate**—are also used [L2652]. Potassium gluconate is believed to be more palatable and non-acidifying than potassium chloride (KCl) [L2658].] |
|
Pamrevlumab
|
DB14952 |
[Pamrevlumab is under investigation in clinical trial NCT00913393 (Study of FibroGen (FG)-3019 in Subjects With Type 2 Diabetes Mellitus and Kidney Disease on ACEi and/or ARB Therapy).] |
|
Etirinotecan pegol
|
DB14951 |
[Etirinotecan pegol is under investigation in clinical trial NCT01663012 (Phase II NKTR-102 In Bevacizumab-Resistant High Grade Glioma).] |
|
Tetragalacturonic acid hydroxymethylester
|
DB13621 |
|
|
PIK3CA
|
DB14954 |
[PIK3CA is under investigation in clinical trial NCT02957266 (Cervical Cancer Radiotherapy by Use of VMAT, Individualized Polyradiosensitization and Interstitial Brachytherapy).] |
|
Selenium (75Se) norcholesterol
|
DB13622 |
|
|
Fabomotizole
|
DB13623 |
|
|
Firtecan pegol
|
DB14953 |
[Firtecan pegol is under investigation in clinical trial NCT01036113 (A Phase 2 Study of EZN-2208 in Patients With Metastatic Breast Cancer).] |
|
BMS-929075
|
DB14950 |
[BMS-929075 is under investigation in clinical trial NCT01525212 (Multiple Ascending Dose Study of BMS-929075 in Hepatitis C Virus (HCV) Infected Patients).] |
|
Piperacillin
|
DB00319 |
[Semisynthetic, broad-spectrum, ampicillin derived ureidopenicillin antibiotic proposed for pseudomonas infections. It is also used in combination with other antibiotics.] |
|
7-methyl-GpppA
|
DB01649 |
|
|
Codeine
|
DB00318 |
[The relief of pain (analgesia) is a primary goal for enhancing the quality of life of patients and for increasing the ability of patients to engage in day to day activities. Codeine, an opioid analgesic, was originally approved in the US in 1950 and is a drug used to decrease pain by increasing the threshold for pain without impairing consciousness or altering other sensory functions. Opiates such as codeine are derived from the poppy plant, _Papaver somniferum_ (Papaveraceae).[A175096]
Codeine is utilized as a central analgesic, sedative, hypnotic, antinociceptive, and antiperistaltic agent, and is also recommended in certain diseases with incessant coughing.[LABEL,A175096]] |
|
Beta-Hydroxyleucine
|
DB02978 |
|
|
N-Acetylmethionine
|
DB01646 |
|
|
Zolmitriptan
|
DB00315 |
[Zolmitriptan is a synthetic tryptamine derivative readily soluble in water.] |
|
N1,N14-Bis((S-Methyl)Isothioureido)Tetradecane
|
DB02979 |
|
|
Capreomycin
|
DB00314 |
[Cyclic peptide antibiotic similar to viomycin. It is produced by Streptomyces capreolus. [PubChem]] |
|
Genistein
|
DB01645 |
[An isoflavonoid derived from soy products. It inhibits protein-tyrosine kinase and topoisomerase-II (DNA topoisomerases, type II) activity and is used as an antineoplastic and antitumor agent. Experimentally, it has been shown to induce G2 phase arrest in human and murine cell lines.
Additionally, genistein has antihelmintic activity. It has been determined to be the active ingredient in <I>Felmingia vestita</I>, which is a plant traditionally used against worms. It has shown to be effective in the treatment of common liver fluke, pork trematode and poultry cestode.
Further, genistein is a phytoestrogen which has selective estrogen receptor modulator properties. It has been investigated in clinical trials as an alternative to classical hormone therapy to help prevent cardiovascular disease in postmenopausal women [A14417].
Natural sources of genistein include tofu, fava beans, soybeans, kudzu, and lupin.] |
