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PAC-14028
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DB12428 |
[PAC-14028 has been used in trials studying the treatment of Skin Pruritus, Papulopustular Rosacea, and Erythematotelangiectatic Rosacea.] |
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Tetramethrin
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DB13752 |
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Somavaratan
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DB12421 |
[Somavaratan has been used in trials studying the treatment of Growth Disorders and Adult Growth Hormone Deficiency.] |
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Cetiedil
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DB13753 |
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Sulforaphane
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DB12422 |
[Sulforaphane is under investigation for the treatment of Autism Spectrum Disorder. It is a naturally occurring isothiocyanate found in high concentration in a variety of broccoli.] |
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Fozivudine Tidoxil
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DB12423 |
[Fozivudine Tidoxil has been used in trials studying the treatment of HIV Infections.] |
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Mephenoxalone
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DB13754 |
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Iocarmic acid
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DB13755 |
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MK-3207
|
DB12424 |
[Mk3207 has been used in trials studying the treatment of Migraine and Migraine Disorders.] |
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Obidoxime
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DB13750 |
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Glycyrrhizic acid
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DB13751 |
[Glycyrrhizic acid is extracted from the root of the licorice plant; _Glycyrrhiza glabra_.[F79] It is a triterpene glycoside with glycyrrhetinic acid that possesses a wide range of pharmacological and biological activities. When extracted from the plant, it can be obtained in the form of ammonium glycyrrhizin and mono-ammonium glycyrrhizin.[T204] Glycyrrhizic acid has been developed in Japan and China as a hepatoprotective drug in cases of chronic hepatitis.[A33062] From January 2014, glycyrrhizic acid as part of the licorice extract was approved by the FDA as an existing food sweetener.[F80] It was approved by Health Canada to be used in over-the-counter products but all the products are currently on the status canceled post marketed.[L1113]] |
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Diazepinomicin
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DB12420 |
[Diazepinomicin has been used in trials studying the treatment of Glioblastoma Multiforme. It is a proprietary first-in-class small molecule with the potential to treat multiple solid tumours like the well known chemotherapeutics, doxorubicin and mitomycin C. Diazepinomicin is a natural product derived from a non-pathogenic micro-organism. Discovered using Thallion’s DECIPHER technology, diazepinomicin has completed preclinical studies conducted by the National Cancer Institute and Thallion to establish safety and efficacy in animal and in vitro models.] |
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Loracarbef
|
DB00447 |
[Loracarbef is a carbacephem antibiotic sometimes grouped together with the second-generation cephalosporin antibiotics. It is marketed under the trade name Lorabid.] |
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8-Aminotheophylline
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DB01778 |
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CoA-S-trimethylene-acetyl-tryptamine
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DB01777 |
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Chloramphenicol
|
DB00446 |
[An antibiotic first isolated from cultures of _Streptomyces venequelae_ in 1947 but now produced synthetically. It has a relatively simple structure and was the first broad-spectrum antibiotic to be discovered. It acts by interfering with bacterial protein synthesis and is mainly bacteriostatic. (From Martindale, The Extra Pharmacopoeia, 29th ed, p106)] |
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Dipivefrin
|
DB00449 |
[Dipivefrin is a prodrug of adrenaline, which is used to treat glaucoma. It is available as ophthalmic solution (eye drops).] |
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Glycerol-2-Phosphate
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DB01779 |
|
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Lansoprazole
|
DB00448 |
[Lansoprazole marketed under the brand Prevacid, is a proton pump inhibitor (PPI) and is structurally classified as a substituted benzimidazole.[A177065] It reduces gastric acid secretion by targeting gastric H,K-ATPase pumps and is thus effective at promoting healing in ulcerative diseases, and treating gastroesophageal reflux disease (GERD) along with other pathologies caused by excessive acid secretion.[A177053]] |
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Betamethasone
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DB00443 |
[A glucocorticoid given orally, parenterally, by local injection, by inhalation, or applied topically in the management of various disorders in which corticosteroids are indicated. Its lack of mineralocorticoid properties makes betamethasone particularly suitable for treating cerebral edema and congenital adrenal hyperplasia. (From Martindale, The Extra Pharmacopoeia, 30th ed, p724)] |