|
Prilocaine
|
DB00750 |
[A local anesthetic that is similar pharmacologically to lidocaine. Currently, it is used most often for infiltration anesthesia in dentistry. (From AMA Drug Evaluations Annual, 1992, p165)] |
|
Isoflurane
|
DB00753 |
[A stable, non-explosive inhalation anesthetic, relatively free from significant side effects.] |
|
Tranylcypromine
|
DB00752 |
[A propylamine formed from the cyclization of the side chain of amphetamine. This monoamine oxidase inhibitor is effective in the treatment of major depression, dysthymic disorder, and atypical depression. It also is useful in panic and phobic disorders (From AMA Drug Evaluations Annual, 1994, p311).
Tranylcypromine is a racemate comprising equal amounts of (1R,2S)- and (1S,2R)-2-phenylcyclopropan-1-amine with the chiral centers both located on the cylopropane ring. An irreversible monoamine oxidase inhibitor that is used as an antidepressant (INN tranylcypromine).] |
|
LTX-315
|
DB12748 |
[LTX-315 has been used in trials studying the treatment of Cancer, Lymphoma, Melanoma, Carcinoma, and Breast Cancer, among others.] |
|
Gamithromycin
|
DB11416 |
|
|
Butylphthalide
|
DB12749 |
[Butylphthalide has been used in trials studying the prevention of Restenosis.] |
|
Florfenicol
|
DB11413 |
[Florfenicol is a fluorinated synthetic analog of thiamphenicol.] |
|
CGI-1842
|
DB12744 |
[JI-101 has been used in trials studying the treatment of Cancer, Colon Cancer, Neuroendocrine, Ovarian Cancer, and Advanced Solid Tumors.] |
|
Haloxon
|
DB11419 |
|
|
GSK-690693
|
DB12745 |
[GSK690693 has been used in trials studying the treatment of Tumor, CANCER, and Lymphoma.] |
|
AKN-028
|
DB12746 |
[AKN-028 has been used in trials studying the treatment of Acute Myeloid Leukemia.] |
|
Tertomotide
|
DB12747 |
[Tertomotide is under investigation in clinical trial NCT01223209 (A Study, Combination, Immunologic Study of LTX-315 as adjunct to tertomotide in Patients Following Curative Surgery for Carcinoma). It is a peptide vaccine that activates the immune system so that it recognizes and kills cancer cells. It is being developed by Pharmexa A/S.] |
|
Gleptoferron
|
DB11417 |
[Colloid solution of ferric hydroxide, dextran & glucoheptonic acid.] |
|
CC-115
|
DB12740 |
[CC-115 has been used in trials studying the treatment of Prostate Cancer, Neoplasm Metastasis, Ewing's Osteosarcoma, Glioblastoma Multiforme, and Chronic Lymphocytic Leukemia, among others.] |
|
DTP-348
|
DB12741 |
[Dtp348 has been used in trials studying the treatment of Solid Tumors and Head and Neck Neoplasms.] |
|
Amuvatinib
|
DB12742 |
[Amuvatinib has been used in trials studying the treatment of Solid Tumors and Small Cell Lung Carcinoma. Amuvatinib is an oral, selective multi-targeted tyrosine kinase inhibitor that suppresses c-MET, c-RET and the mutant forms of c-KIT, PDGFR and FLT3. Amuvatinib also suppresses Rad51 protein, a critical component of double-stranded DNA repair in cancer cells.] |
|
Z-160
|
DB12743 |
[Z160 has been used in trials studying the treatment of Postherpetic Neuralgia and Lumbosacral Radiculopathy.] |
|
Fenthion
|
DB11412 |
[Fenthion is an _organothiophosphate_ drug used as an insecticide, avicide, and acaricide. Its mode of action is explained by cholinesterase enzyme inhibition, which is similar to other organophosphates. Fenthion is listed as a restricted use compound by the United States Environmental Protection Agency due to its potential to cause cholinesterase inhibition in humans and animals.] |
|
Fenprostalene
|
DB11411 |
|
|
Fenbendazole
|
DB11410 |
[Fenbendazole is a benzimidazole that presents a wide spectrum anthelmintic effect. It is used against a number of gastrointestinal parasites including giardia, roundworms, hookworms, whipworms, the Taenia genus of tapeworms, pinworms, aelurostrongylus, paragonimiasis, strongyles, and Strongyloides. Fenbendazole is approved to be administered under veterinary to sheep, cattle, horses, fish, dogs, cats, rabbits and seals.] |
